BOOK CHAPTERS AND OTHER PUBLICATIONS

 

 

  1. Cobelli C., Lepschy A., Romanin Jacur G.: Structural identifiability of biological compartmental systems: digital computer implementation of a testing procedure. In Optimization Techniques, ed. J. Cea, Springer-Verlag, Berlin-Heidelberg, 1976, Part I, 88-102.

  2. Cobelli C., Federspil G., Pacini G., Salvan A., Scandellari C.: A non-linear model of the carbohydrate metabolism regulation system for oral and intravenous glucose tolerance test. In Proc. IFAC Symposium on Control Mechanisms in Bio- and Eco-systems, Leipzig, DDR, 1977, vol. 1, 132-139.

  3. Cobelli C., Lepschy A., Romanin Jacur G.: Identifiability problems in biological systems. In Identification and System Parameter Estimation, (Proc. 4th IFAC Symposium, Tblisi, 1976) ed. N.S. Rajbman, North-Holland, Amsterdam 1978, Part I, 525-535.

  4. Cobelli C., Salvan A.: Reliability of parameter estimation in biological compartmental models. A computer analysis of several factor influencing the estimates. In Identification and System Parameter Estimation, (Proc. 4th IFAC Symposium, Tblisi, 1976) ed. N.S. Rajbman, North- Holland, Amsterdam 1978, Part I, 537-547.

  5. Cobelli C., Morato L., Salvan A., Toffolo G.: Parameter estimation in biological stochastic compartmental models with the transport rate parameters considered as stochastic processes. Validation on simulated data. In Proc. Summer Computer Simulation Conf., Newport Beach, Calif., Usa, 1978, 636-640.

  6. Cobelli C., Lepschy A., Milo S.: Model of societal and historical phenomena. In Proc. of the IV Italo-Polish Symposium on Mathematical System Theory in Management and Economics, Bergamo, Italy,1978.

  7. Cobelli C., Lepschy A., Romanin Jacur G.: Identifiability of time-variant compartmental models of biological processes. In A Link between Science and Applications of Automatic Control (Proc. 7th IFAC World Congress, Helsinki, 1978) ed. A. Niemi, Pergamon Press, Oxford, Vol. I, 509-512, 1979.

  8. Cobelli C., Lepschy A., Milo S.: A tentative model of the dynamic behavior of society. In Progress in Cybernetics and System Research Scienze, Lettere ed Arti, vol. 5, eds. Trappl. R. and F. de Hanika, Hemisphere Publ., New York, 1979, 190-193.

  9. Cobelli C., Madonna A., Ruggeri A.: Testing of model structures in identification of metabolic systems. In Proc. 18th IEEE Conf. Dec. Contr., Lauderdale, Florida (USA), 1979, vol. 1, 516-517.

  10. Cobelli C., Lepschy A., Romanin Jacur G.: Structural identifiability of linear compartmental models. In Theoretical Systems Ecology, ed. E. Halfon, Academic Press, New York, 237-258, 1979.

  11. Cobelli C., Lepschy A., Romanin Jacur G.: Identification experiments and identifiability criteria for compartmental systems. In Compartmental Analysis of Ecosystem Models, eds. J.H. Matis, B.C. Patten, G.C. White, Statistical Ecology Program, vol. 10, International Cooperative Publ. House, Fairland, Md. USA. 99-123,1979.

  12. Bergman R.N., Bortolan G., Cobelli C., Toffolo G.: Identification of a minimal model of glucose disappearance for estimating insulin sensitivity. In Identification and System Parameter Estimation, (Proc. 5th IFAC Symposium, Darmstadt, 1979) ed. R. Isermann, Pergamon Press, Oxford 1979, vol. 2, 883-890.

  13. Carson E.R., Cobelli C., Finkelstein L.: The identification of metabolic systems. A review. In Identification and System Parameter Estimation. (Proc. 5th IFAC Symposium, Darmstadt, 1979) ed. R. Isermann, Pergamon Press, Oxford 1979, vol. 1, 151-171.

  14. Cobelli C., Federspil G., Pacini G., Salvan A., Scandellari C.: Modelling and simulation of the blood glucose regulation system. In Simulation of Systems, eds. L. Dekker, G. Savastano, G.C. Van Steenkiste, Elsevier- North Holland, Amsterdam, 1979, 675-684.

  15. Cobelli C., Lepschy A., Romanin Jacur G.: Identifiability results on some constrained compartmental systems. Math. Biosci. 47: 173-195, 1979.

  16. Bergman R.N., Toffolo G., Bowden C.R., Cobelli C.: Minimal modeling, partition analysis, and identification of glucose disposal in animals and man. In Proceed. IEEE 1980 Int. Conf. on Cybernetics and Society, New York, USA, 1980, 129-135.

  17. Cobelli C., Pacini G., Salvan A.: On a simple model of insulin secretion. Med. Biol. Eng. Comput. 18: 457-463, 1980.

  18. Cobelli C., Langella G., Lepschy A.: A system approach to the modeling of voting behaviour. In Proc. 5° Polish- Italian Symposium on System Theory in Management and Economics, Torun, 1980, 189-199.

  19. Bergman R.N., Cobelli C.: Minimal modeling, partition analysis and the estimation of insulin sensitivity. Fed. Proc. 39: 110-115, 1980.

  20. Cobelli C., Lepschy A., Romanin Jacur G.: Identifiability in tracer experiments. Fed. Proc. 39: 91-96, 1980.

  21. Cobelli C.: Modeling and identification of metabolic systems. In Medical Physics, ed. J.R. Greening, North- Holland, Amsterdam 1981, 481-521.

  22. Cobelli C., Pacini G., Ruggeri A., Del Prato S., Duner E., Nosadini R., Tiengo A.: Algorithms for closed-loop glucose control (artificial pancreas) in diabetes. A novel noninvasive approach for their comparative evaluation based on mathematical modeling. In Control Science and Technology for the Progress of Society, (Proc. 8th IFAC Triennal World Congress, Kyoto 1981) ed. H. Akashi, Pergamon Press, Oxford, 1981, 3711-3716.

  23. Bergman R.N., Bowden C.R., Cobelli C.: The minimal model approach to quantification of factors controlling glucose disposal in man. In Carbohydrate Metabolism. Quantitative Physiology and Mathematical Modeling, C. Cobelli, R.N. Bergman, eds., Wiley, Chichester, 1981, 269-296.

  24. Okolicsanyi L., Orlando R., Venuti M., Cobelli C., Ruggeri A., Pacini G.: Observations on the mechanism of fasting hyperbilirubinemia. In Familial Hyper-bilirubinemia. Ed. L. Okolicsanyi, Wiley, Chichester, 1981, 147-155.

  25. Ventura E., Zeneroli M.L., Rocchi E., Okolisanyi L., Orlando R., Venuti M., Cobelli C., Pacini G., Ghidini O.: Crystalline bilirubin kinetics in Gilbert's Syndrome: a multicenter study. In Familial Hyper-bilirubinemia, ed. L. Okolicsanyi, Wiley, Chichester, 1981, 109-119.

  26. Cobelli C., Ruggeri A., Toffolo G., Okolicsanyi L., Venuti M., Orlando R.: BSP vs bilirubin kinetics in Gilbert's syndrome. In Familial Hyper-bilirubinemia, ed. L. Okolicsanyi, Wiley, Chichester, 1981, 121-131.

  27. Venuti M., Nassuato G., Lirussi F., Okolicsanyi L., Cobelli C., Pacini G., Danieli R.: Antipiryne and galactose kinetics in Gilbert's syndrome. In Familial Hyper-bilirubinemia, ed. L. Okolicsanyi, Wiley, Chichester, 1981, 181-186.

  28. Cobelli C.: A priori identifiability analysis in pharmacokinetic experiment design. In Kinetic Data Analysis. Design and Analysis of Enzyme and Pharmaco- kinetic Experiments. Laszlo Endrenyi, ed. Plenum Press, New York, 1981, 181-208.

  29. Leaning M.S., Uttamsingh R.J., Carson E.R., Cobelli C., Finkelstein L.: A model of the human renal-artificial kidney system: methodological aspects of model validation. In A General Survey of Systems Methodology (Proc. 26th Annual Meeting of the SGRS), ed. L. Troncale, Society for General Systems Research, Louisville, Kentucky, 1981, pp. 508-516.

  30. Cobelli C., Toffolo G., Nosadini R.: Mathematical models of ketone body kinetics in the human. Experiment design and their identification/validation. In Identification and System Parameter Estimation (Proc. 6th IFAC Symposium, Arlington, 1982), eds. G.A. Bekey and G.N. Saridis, Pergamon, Oxford, 1982, vol. 1, 222-227.

  31. Carson E.R., Cobelli C., Finkelstein L.: Integrated methodology for model formulation, identification and validation. In Identification and System Parameter Estimation (Proc. 6th IFAC Symposium, Arlington, 1982), eds. G.A. Bekey and G.N. Saridis, Pergamon, Oxford, 1982, vol. 2, 884-889.

  32. Cobelli C., Mari A., Thomaseth K.: Simple vs comprehensive models of glucose/insulin dynamic interactions in the whole organism. Role of identification and validation. In Identification and System Parameter Estimation (Proc. 6th IFAC Symposium, Arlington, 1982), eds. G.A. Bekey and G.N. Saridis, Pergamon, Oxford, 1982, vol. 2, 896-901.

  33. Cobelli C., Carson E.R., Finkelstein L.: Modeling metabolic and endocrine systems: an integrated approach to model formulation, identification and validation. In Proc. 10th IMACS World Congress on Systems Simulation and Scientific Computation, Montreal, Canada, August 8-13, 1982, vol. 3, 214-216.

  34. Bossi A., Cobelli C., Colussi L., Romanin Jacur G.: Numerical and symbolic algorithms to solve the problem of structural identifiability. In Atti del Congresso Annuale AICA, 1982, 485-495.

  35. Cobelli C., Ruggeri A.: Open loop insulin infusion systems in diabetes. A modeling study of intravenous delivery strategies. In Proc. IV World Congress on Medical Informatics MEDINFO83, Eds. J.H. Van Bemmel, M.J. Ball, O. Wigertz, North-Holland, Amsterdam, 1983, Part 2, 891-894.

  36. Pacini G., Bergman R.N., Cobelli C.: Minimal models of carbohydrate metabolism for automatic control of the blood sugar and for estimation of metabolic parameters. In Proc. 1983 Summer Computer Simulation Conference, Vancouver, Canada, The Society for Computer Simulation, North- Holland, Amsterdam, 1983, vol. 1, 593-597.

  37. Bergman R.N., Pacini G., Finegood D.T., Cobelli C.: The minimal modeling approach: application for estimating insulin sensitivity during automatic control of the blood sugar. In Artificial Systems for Insulin Delivery, eds. P. Brunetti, K.G.M.M. Alberti, A.M. Albisser, K.D. Hepp and M. Massi Benedetti, Raven Press, New York, 1983, 411- 419.

  38. Cobelli C.: Diabetes management: insight from mathematical modeling. In Objective Medical Decision-Marking: System Approach in Acute Disease, eds. J.E.W. Beneken, S.M. Lavelle, Springer, Berlin, 1983, 117-130.

  39. Cobelli C., Bergman R.N.: Mathematical modeling of glucoseinsulin relationships in vivo. In Artificial Systems for Insulin Delivery, eds. P. Brunetti, K.G.M.M. Alberti, A.M. Albisser, K.D. Hepp and M. Massi Bendetti, Raven Press, New York, 1983, 21-31.

  40. Cobelli C., Toffolo G., Nosadini R., Avogaro A., Tiengo A.: A new model-based approach for studying the turnover of ketone bodies in vivo. In Diabetes, Obesity and Hyperlipidemias II, eds. G. Crepaldi, P.J. Lefebre, D.J. Galton, Academic Press, London, 1983, 257-267.

  41. Nosadini R., Toffolo G., Marescotti C., Cobelli C., Mollo F., Avogaro A., Enzi G., Benetton M.G.: A model of ketone body kinetics in insulin-dependent diabetics. In Diabetes, Obesity and Hyperlipidemias II, eds. G. Crepaldi, P.J. Lefebre, D.J. Galton, Academic Press, London, 1983, 275-279.

  42. Cobelli C., Carson E.R., Finkelstein L.: An integrated approach for biosystem modelling in endocrinology and metabolism. Some fundamentals and its relevance in developing useful models of the glucose regulating system. In Modelling and Data Analysis in Biotechnology and Medical Engineering, eds. G.C. Vansteenkiste, P.C. Young, North-Holland, Amsterdam, 1983, 3-20.

  43. Cobelli C., Carson E.R., Finkelstein L., Leaning M.S.: Model formulation, identification and validation: an integrated approach for the study of physiological systems. In Mathematical Modelling in Science and Technology, ed. X.J.R. Avula, Pergamon Press, Oxford, 1983, 751-756.

  44. Carson E.R., Cobelli C.: Model-based measurement for innovation in biomedical equipment. In UN Economic Commission for Europe Seminar on Innovation in Biomedical Equipment, Budapest, 1983, paper R.30.

  45. Carson E.R., Cobelli C., Finkelstein L.: The Mathematical Modeling of Endocrine-Metabolic Systems. Model Formulation, Identification and Validation. Wiley, New York, 1983, pgg. 394.

  46. Nosadini R., Avogaro A., Cobelli C., Toffolo G., Marescotti C., Mollo F., Benetton M., Tiengo A., Enzi G.: The kinetics of ketone bodies in obese and insulin- dependent diabetic subjects. In Recent Advances in Obesity and Diabetes Research, eds. N. Melchionda, D.L. Horwitz, D.S. Schade, Raven Press, New York, 1984, 293-308.

  47. Cobelli C., Mari A., Toffolo G.: The glucose regulation system in healthy and disease states: the use of models for understanding and control. In A Bridge between Control Science and Technology (Preprints 9th IFAC World Congress, Budapest), eds. J. Gertler and L. Keviczky, Pergamon Press, Oxford, vol. II, 92-96, 1984.

  48. Leaning M.S., Carson E.R., Cobelli C., Finkelstein, L.: Validity of measurements obtained by model identification and parameter estimation. In Proc. IMEKO Symposium on Measurement and Estimation, (Bressanone-Brixen, Italy), 1984, 63-66.

  49. Cobelli C., DiStefano III J.J., Ruggeri A.: Optimal experiment design in clinical medicine: a computer program and applications to compartmental models. In Proc. 8th Ann. Symp. on Computer Applications in Medical Care. IEEE, New York, 1984, 132-134.

  50. Cramp D.G., Carson E.R., Cobelli C.: Formulation, identification and validation of mathematical models for plasma protein metabolic studies. In Pathophysiology of Plasma Protein Metabolism, ed. G. Mariani, McMillan, London, 1984, 35-70.

  51. Thomaseth K., Young P.C., Cobelli C.: Recursive-iterative IV estimation of multiple-input transfer function models. In Prepr., 7th IFAC Symp. on Identification and System Parameter Estimation, eds. H.A. Barker and P.C. Young, Pergamon Press, Oxford, 1985, vol. 2, 1345-1350.

  52. Cobelli C., Toffolo G.: Compartmental and noncompartmental models as candidate classes for kinetic modeling. Theory and computational aspects. In Mathematics and Computers in Biomedical Applications, eds, J. Eisenfeld and C. De Lisi, Elsevier, New York, 1985, 219-236.

  53. Cobelli C., Toffolo G.: Theoretical aspects and practical strategies for the identification of unidentifiable compartmental systems. In Prep. 7th IFAC Symposium on Identification and System Parameter Estimation, eds. H.A. Barker and P.C. Young, Pergamon Press, Oxford, 1985, vol. 2, 1409-1414.

  54. Cobelli C., Ruggeri A., Thomaseth K.: Optimal input and sampling schedule for physiological system identification. Some theoretical and in vivo results on a compartmental model of glucose kinetics. In Mathematics and Computers in Biomedical Applications, eds. J. Eisenfeld and C. De Lisi, Elsevier, New York, 1985, 161-172.

  55. Cobelli C.: Identification of endocrine-metabolic and pharmacokinetic systems. In Prepr. 7th IFAC Symposium on Identification and System Parameter Estimation, eds. H.A. Barker and P.C. Young, Pergamon Press, Oxford, 1985, vol. 1, 45-57.

  56. Cobelli C., Thomaseth K.: Experiment design, identification and validation of simple and complex models of endocrinemetabolic systems. In Mathematics in Biology and Medicine, eds. V. Capasso, E. Grosso and S. C. Paveri-Fontana, Springer, Berlin, 1985, 208-219.

  57. Carson E.R., Cobelli C., Cramp D.G.: The role of model- based measurement in the design of medical instrumentation. In Proc. IMEKO 85-10th World Congress, Prague, Czechoslovakia, 1985, N. 331: 1-8.

  58. Avogaro A., Nosadini R., Trevisan R., de Kreutzenberg S., Duner R., Toffolo G., Cobelli C., Baccaglini V., Tiengo A., Tremolada C., Fioretto P., Crepaldi G.: The effects of continuous subcutaneous and peritoneal insulin treatment on glucose and ketone bodies metabolism in insulin- dependent diabetic subjects. In Diabetes, Obesity, and Hyperlipidemia - III, eds. G. Crepaldi, A. Tiengo, A. Baggio, Elsevier, Amsterdam, 1985, 459-470.

  59. Cobelli C., Toffolo G.: Compartmental vs noncompartmental modeling of ketone body kinetics. In Mathematics in Biology and Medicine, eds. V. Capasso, E. Grosso, and S.C. Paveri- Fontana, Springer, Berlin, 1985, 415-420.

  60. Toffolo G., Cobelli C.: Kinetic modeling of stable isotope data: new developments. In Proc. 3rd IMEKO International Conference Measurements in Clinical Medicine, Edinburgh, UK, 245-250, 1986.

  61. Cobelli C., Lepschy A., Romanin Jacur G., Viaro U.: Compartmental analysis and its use in management and quantitative economics. In System Theory and Mathematical Economics, eds. P. Caravani, K. Cuchocki, Pitagora, Bologna, 1986, 189-218.

  62. Cobelli C., Mari A., de Kreutzenberg S., Duner R., NosadiniR., Tiengo A., Jensen I., Heding L.G.: Reconstructing the absorption rate of subcutaneous insulin: a novel approach based on deconvolution. In Diabetes 1985, eds. M. SerranoRios and P.J. Lefebvre, Excerpta Medica, Amsterdam, 1986, 862-866.

  63. Nosadini R., Avogaro A., Duner E., Trevisan R., Tremolada C., Baccaglini U., Nosadini A., Ambrosio F., Merkel C., Cobelli C., Toffolo G.: Ketone body formation can take place outside liver in normal dog. In Diabetes 1985, eds. M. Serrano-Rios and P.J. Lefebvre, Excerpta Medica, Amsterdam, 1986, 347-354.

  64. Thomaseth K., Cobelli C.: Optimal input studies for physiological systems identification. In Proc. 3rd IMEKO Conference on Measurements in Clinical Medicine, Edinburgh, U.K., 241-244, 1986.

  65. Cobelli C., Thomaseth K.: Assessing output measurement optimality in physiological system identification by a design measure approach. In Proc. 25th IEEE Conf. Dec. Contr., Athens, Greece, 1986, vol. 1, 282-286.

  66. Cobelli C.: Mathematical models of insulin, ketone bodies and glucose kinetics in diabetes: their use for understanding and assessing metabolism and its control. In Objective Medical Decision-Making, ed. D.D. Tsiftsis, Springer, Berlin, 130-140, 1986.

  67. Caumo A., Cobelli C., Saccomani M.P.: Insulin kinetics: insight from compartmental modeling and deconvolution. In Proc. IEEE 7th Ann. Conf. Engng. Med. Biol. Society, Forth Worth, Texas, 1986, 713-718.

  68. Cobelli C., Thomaseth K.: Maximally informative designs in physiological modelling based on optimality-criteria gradients. In Prepr. 10th IFAC World Congress on Automatic Control, ed. R. Isermann, Pergamon Press, Oxford, 1987, vol. 10, 231-236.

  69. Cobelli C., Mari A.: Models for the estimation of glucose fluxes in non-steady state from concentration measurements. In Prepr. 10th IFAC World Congress on Automatic Control, ed. R. Isermann, Pergamon Press, Oxford, 1987, vol. 5, 1-12.

  70. Cobelli C., Mari A., Toffolo G., Cherrington A.D., McGuiness O.P.: Dynamic control of insulin on glucose kinetics: tracer experiment design and time-varying interpretative models. In Prepr. 10th IFAC World Congress on Automatic Control, ed. R. Isermann, Pergamon Press, Oxford, 1987, vol. 5, 25-30.

  71. Cobelli C., Toffolo G.: Theoretical aspects and practical strategies for the identification of unidentifiable compartmental systems. In Identifiability of Parametric Models, ed. E. Walter, Pergamon, Oxford, 1987, 85-91.

  72. Cobelli C., Toffolo G., Nosadini R.: Ketone body metabolism modeling. In Systems and Control Encyclopedia, ed. M.G. Singh., Pergamon, Oxford, 1987, 2628-2631.

  73. Cobelli C., Bergman R.N.: Glucose Regulation: Modeling. In Systems and Control Encyclopedia, ed. M.G. Singh., Pergamon, Oxford, 1987, 2021-2025.

  74. Cobelli C.: Identification of endocrine-metabolic and pharmacokinetic systems. In Control Aspects of Biomedical Engineering, ed. M. Nalecz, Pergamon, Oxford, 1987, 235-249.

  75. Caumo A., Micossi P., Cobelli C.: Models for measuring hepatic glucose production from labelled IVGTT. In Prepr. 1st IFAC Symposium on Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1988, 618-623.

  76. Pacini G., Cobelli C.: Development in minimal modeling of IVGTT: the measurement of glucose production. In Advances in Biomedical Measurement, eds. E.R. Carson, P. Kneppo, I. Krekule, Plenum Press, New York, 1988, 291-296.

  77. Thomaseth K., Cobelli C.: Optimal input design for physiological systems identification: theory and practice. In Proc. 12th IMACS World Congress, eds. R. Vichnevetsky, P. Borne, J. Vignes, 1988, vol. 2, 514-516.

  78. Cobelli C., Mari A.: Models for the estimation of glucose fluxes in non-steady state from concentration measurements. In Automatic Control World Congress 1987, ed. R. Isermann, 1988, vol. V, 1-12.

  79. Cobelli C., Mari A., Toffolo G., Cherrington A.D., McGuinness O.P.: Dynamic control of insulin on glucose kinetics: tracer experiment design and time-varying interpretative models. In Automatic Control World Congress 1987, ed. R. Isermann, 1988, vol. V, 25-30.

  80. Cobelli C., Toffolo G.: Whole body and regional kinetic models to quantitate glucose and aminoacid metabolism in man from tracer data. In Positron Emission Tomography in Clinical Research and Clinical Diagnosis, eds. C. Beckers, A. Goffinet, A. Bol, Kluwer Academic Publishers, Dordrecht, 1989, 137-147.

  81. Mari A., Cobelli C., Cherrington A.D., McGuinness O.P.: A model for the study of glucose kinetics in nonsteady state. In Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1989, 357-372.

  82. Pacini G., Cobelli C.: A minimal model of C-peptide secretion and kinetics: fundamentals and clinical use. In Modelling and Control of Physiological Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1989, 363-370.

  83. Ruggeri A., Cobelli C.: Optimal sampling schedule design may reveal inadequacy of model structure: a case study on the minimal model of glucose disappearance. In Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1989, 121-125.

  84. Ruggeri A., Cobelli C.: A reduced sampling schedule for identifying model-based parameters of glucose metabolism: design and validation. In MEDINFO 89 - Proc. Sixth World Conference on Medical Informatics, eds. B. Barber, D. Cao, D. Qin, G. Wagner, North-Holland, Amsterdam, 1989, Part 1, 533-537.

  85. Ruggeri A., Cobelli C., Mussap M., Nemetz L., Plebani M., Zaninotto M., Burlina A.: Evaluation of an expert system in laboratory medicine. In Proc. V Medit. Conf. on Med. & Biol. Eng. "MEDICON 89", eds. G. Nikiforidis, N. Pallikarakis, B. Proimos, Patras, 1989, 274-275.

  86. Ruggeri A., Cobelli C., Toffolo G., Hetenyi G.: A time- varying compartmental model to assess non-steady state glucose kinetics in hypoglycemia from tracer data. In Proc. 11th Ann. Int. Conf. IEEE- EMBS, eds. Y. Kim and F.A. Spelman, IEEE, New York, 1989, Part 1, 258-259.

  87. Saccomani M.P., C. Cobelli, Gabana A., Ferrannini E., Bonadonna R., Gelfand R.A., DeFronzo R.A.: Modeling glucose kinetics in vivo in the human forearm: rationale and a dual tracer study. In Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1989, 345-350.

  88. Saccomani M.P., Cobelli C., Luzi L., Matthews D., Biolo G., Tessari P.: Leucine metabolism in man: insight from compartmental modeling In Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1989, 377-383.

  89. Thomaseth K., Cobelli C.: Optimal input design for physiological systems identification: theory and practice. In Modeling and Simulation of Systems, eds. P. Breedveld, G. Dauphin-Tanguy, P. Borne, S.G. Tsafestas, J.C. Balzer, AG Scientifc Publishing Co., 1989, 201-205.

  90. Thomaseth K., Cobelli C., Balzan I., Bellavere F.: Heart rate spectral analysis for assessing autonomic neuropathy. In Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford 1989, 501-506.

  91. Toffolo G., Cobelli C., Bier D.M., Nosadini R., Avogaro A.: Compartmental modeling of stable isotope tracer data: the general non linear, the linearized and the linear case. In Modelling and Control in Biomedical Systems, eds. C. Cobelli, L. Mariani, Pergamon, Oxford, 1989, 139-143.

  92. Thomaseth K., Cobelli C., Rizzoli G., Gallucci V.: Closed loop control of arterial blood pressure by nitroprusside infusion: experience with a used-friendly bedside computer. Medicina e Informatica 6: 191-194, 1989.

  93. Caumo A., Micossi P., Cobelli C.: Models for measuring hepatic glucose production from labelled IVGTT. In Modelling and Control in Biomedical Systems, eds. Cobelli C., Mariani L, Pergamon, Oxford, 1989, 339-344.

  94. Caumo A., Cobelli C.: Insulin action on glucose kinetics: new developments from a two-compartment minimal model. In Proc. 12th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, USA, 1990, Part 3/5, 1002-1003.

  95. Cobelli C., Bier D.M., Ferrannini E.: Modeling glucose metabolism in man: theory and practice. In Computers and Quantitative Approaches to Diabetes, eds. J. Beyer, J. Schretzenmeir, E.W. Kraegen, G. Thieme Verlag, Stuttgart, 1990 (Horm. Metab. Res. Suppl.24), 1-10

  96. Cobelli C., Caumo A.: Models to assess masses, fluxes, and regulatory interactions of an endocrine control system: the glucose-insulin prototype. In Computers in Endocrinology, eds. G. Forti, V. Guardabasso, D. Rodbard, Raven Press, New York, 1990, 105-121.

  97. Ruggeri A., Cobelli C., Caumo A., Hetenyi G.: Estimation of non-steady state hepatic glucose production by deconvolution with a time-varying compartmental model. In Proc. 12th Ann. Int. Conf. IEEE- EMBS, IEEE, New York, USA, 1990, Part 3/5, 1000-1001.

  98. Saccomani M.P., Cobelli C.: A model of leucine kinetics: a priori identifiability and minimal input-output configuration. In Prepr. 11th IFAC World Congress, eds. V. Utkin, U. Jaskoo, Pergamon Press, Oxford, 1990, vol. 4, 28-32.

  99. Saccomani M.P., Cobelli C.: A flow-compartmental model to measure glucose transport and insulin control upon it in the human skeletal muscle. In Proc. 12th Ann. Conf. of IEEE-EMBS, IEEE, New York, 1990, Part 1, 464-465.

  100. Thomaseth K, Cobelli C.: Conventional and minimax input design for achieving tracer steady state in kinetic studies. In Proc. 6th IMEKO Conference on Measurement in Clinical Medicine, Scientific Society of Mesurement and Automation, Budapest, 1990, 115-117.

  101. Zerman A., Cobelli C., Sacca' L.: A compartmental model of lactate kinetics in humans: role of sites of tracer administration and sampling. In Proc. 12th Ann. Conf. of IEEE-EMBS, IEEE, New York, 1990, Part 3, 959-960.

  102. Cobelli C., Saccomani M.P.: Domain of validity of classical models of leucine metabolism assessed by compartmental modeling. Math. Biosci. 107: 3-20, 1991.

  103. Thomaseth K., Cobelli C.: Robust input design for achieving in minimum time tracer steady in compartmental system. In Prepr. 9th IFAC Symp. on Identification and System Parameter Estimation, eds. C. Banyasz, L. Keviczky, Akaprint, Budapest, 1991, vol 1, 791-796.

  104. Toffolo G., Cobelli C.: State and output variables for model identification in stable isotope tracer studies. In Prepr. 9th IFAC Identification and System Parameter Estimation, eds. C. Banyasz, L. Keviczky, Budapest, Akaprint, 1991, vol. 1, 338-347.

  105. Scandellari C., Cobelli C.: Glucose metabolism modelling. Biochimica Clinica 15: 346-349, 1991.

  106. Saccomani M.P., Caveggion E., Cobelli C., Bonadonna R.: Kinetics of bicarbonate in humans: identification and validation of a three-compartment model. In Prepr. 9th IFAC Symposium on Identification and System Parameter Estimation, eds. C. Banyasz, L. Keviczky, Budapest, Akaprint, 1991, Part 1, 797-802.

  107. Saccomani M.P., Cobelli C., Bonadonna R.: Extension of the flow-compartmental model of glucose trasport kinetics to measure glucose metabolism in the human skeletal muscle. In Proc. 13th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, 1991, vol. 13, 2291-2292.

  108. Zerman A., Cobelli C., Caumo A., Butler P., Rizza R.: Hepatic glucose production estimated by tracer model and deconvolution: role of endogenous glucose concentration. In Proc. 13th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, 1991, Part 3, 2289-2290.

  109. Dobbins R., Cherrington A., Cobelli C., Mari A.: A model of glucagon control of hepatic glucose production. In Proc. 13th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, 1991, vol. 13, 2293-2294.

  110. Ruggeri A., Cobelli C.: The minimal model of glucose disappearance: relaxing the error-free insulin input assumption. In Proc. 13th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, 1991, Part 3, 2287-2288.

  111. Saccomani M.P., Cobelli C.: A model of leucine kinetics: a priori identifiability and minimal input-output configuration. In Automatic Control (Proc. 11th IFAC World Congress, Tallin, Estonia, USSR, 1990), eds. U. Jaaksoo, V.I. Utkin, Pergamon Press, Oxford, 1991, vol. 2, 225-229.

  112. Saccomani M.P., Sattier R., D'Angio' L., Audoly S., Cobelli C.: An automatized topological method to test a priori global identifiability of a class of compartmental models. In Proc. 14th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, 1992, Part 6, 2282-2283.

  113. Zerman A., Caumo A., Butler P., Rizza R., Cobelli C.: Validation of a new tracer model of non-steady-state glucose kinetics. In Proc. 14th Ann. Int. Conf. IEEE-EMBS, IEEE, New York, 1992, Part 6, 2265-2266.

  114. Vicini P., Saccomani M.P., Bonadonna R., Cobelli C.: A multi-region distributed parameter model for measuring glucose kinetics in the human skeletal muscle from indicator-dilution data. In Proc. VI Medit. Conf. Med. Biol. Eng, eds. F. Denoth, M. Bracale, Area di Ricerca CNR di Pisa, 1992, vol. 1, 73-80.

  115. Cobelli C., Toffolo G., Foster D.: Tracer-to-tracee ratio for analysis of stable isotope tracer data: link with radioactive kinetic formalism. Am. J. Physiol. 263: E597-E606, 1992.

  116. Sarti E., Cobelli C.: Controllo di sistemi metabolici. In Bioelettronica e Nanotecnologie per la Bioingegneria, eds. D. De Rossi, M. Grattarola, Pàtron, Bologna, 1992, 11, 101-119.

  117. Cobelli C., Saccomani M.P., Matthews D.E.: Evolution of models of leucine kinetics for measuring protein turnover. In Protein Metabolism in Diabetes Mellitus, ed. K.S. Nair, Smith-Gordon, London, 1992, 69-77.

  118. Cobelli C., Saccomani M.P.: Models for studying the kinetics of materials in living systems. In Mathematics Applied to Biology and Medicine, eds. J. Demongeot, V. Capasso, Wuerz Publishing, Winnipeg, Canada, 1993, 373-385.

  119. Reboldi G.P., Ruggeri A., Quintaliani G., Buoncristiani U., Bueti A., Santeusanio F., Cobelli C., Brunetti P.: Effect of different immunosuppressive regimens of glucose tolerance and insulin secretion in non-diabetic kidney-transplanted patients. In Current Topics in Diabetes Research. Frontiers in Diabetes, eds. F. Belfiore, R.N. Bergman, G.M. Molinatti, Karger, Basel, vol. 12, 1993, 267-271.

  120. Foster D., Barrett P., Beltz W., Cobelli C., Golde H., Jacquez J., Phair R., Ruggeri A., Saccomani M.P., Shames D., Toffolo G.: SAAM II: a reengineered, menu-driven SAAM for enhancing biokinetic applications. In Simulation in Health Sciences and Services, eds. J. Anderson, M. Katzper, The Society for Computer Simulation, 1993, 109-114.

  121. Sparacino G., Sturis J., O'Meara N., Byrne M., De Nicolao G., Polonsky K., Cobelli C.: A deconvolution method to quantify rapid pulses in insulin secretion. In Proc. 15th Ann. Int. Conf. IEEE-EMBS, vol. 15, IEEE, New York 1993, 536-537.

  122. D'Angio' L., Audoly S., Bellu G., Saccomani M.P., Cobelli C.: Structural identifiability of nonlinear systems: algorithms based on differential ideals. In Proc. SYSID '94, 10th IFAC Symposium on System Identification (M.Blanke and T.Soderstrom, eds.), vol. 3, (Copenhagen, Denmark), 13-18, Danish Automation Society, 1994.

  123. Foster D.M., Barrett P.H.R., Bell B.M., Beltz W.F., Cobelli C., Golde H., Jacquez J.A., Phair R.D., Ruggeri A., Saccomani M.P., Schumitzky A., Toffolo G.: Using SAAM II to model kinetic and pharmacokinetic data. In Proc. Simulation in Health Sciences Conf., (San Diego), 87-90, Society for Computer Simulation, 1994.

  124. Saccomani M.P., Audoly S., D'Angio' L., Sattier R., Cobelli C.: PRIDE: a program to test a priori global identifiability of linear compartmental models. In Proc. SYSID '94, 10th IFAC Symposium on System Identification (M.Blanke and T.Soderstrom, eds.), vol. 3, (Copenhagen, Denmark), 25-30, Danish Automation Society, 1994.

  125. Bettini F., Caumo A., Cobelli C.: Minimal models in the meal-like protocols: simulation studies to assess precision and physiological plausibility of parameter estimates. In Basic & Applied Biomedical Engineering. Building Blocks for Health Care. Proc. 17th Annual International Conference of the IEEE-EMBS, a cura di F.A. Roberge e R.E. Kearney, Montreal (CAN), Ed. New York, IEEE, 1995, 1361-1362.

  126. Cobelli C., Saccomani M.P.: Compartmental models of physiologic systems. In The Biomedical Engineering Handbook, a cura di J.D. Bronzino, CRCR Press & IEEE Press, Boca Raton, Florida, USA, 1995, 2375-2385.

  127. Saccomani M.P., Cobelli C.: The Buchberger algorithm to study the a priori identifiability of biological systems models. In Proc. 2nd IMACS Conf. on Applications of Computer Algebra, Research Institute for Symbolic Computation, Austria, 73-75, 1996.

  128. Sarti E., Cobelli C.: Recent developments and open problems in feedback control of the glucose system in diabetes. In Biomedical and Life Physics, ed. Dhanjoo N. Ghista, Vieweg, 1996, 431-444.

  129. Bettini F., Caumo A., Rizza R., Cobelli C.: Models of glucose disposal: estimation of glucose effectiveness with an optimal protocol. In Proc. of the 18th IEEE/EMBS Annual Conference, Amsterdam, 1996, 592-593.

  130. Caumo A., Vicini P., Cobelli C.: Minimal models of glucose disappearance: effect of undermodeling assessed by Monte Carlo simulation. In Proc. Third IFAC Symposium on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 89-90, 1997.

  131. Chinello C., Vicini P., Bonadonna R.C., Cobelli C.: Estimation of flow heterogeneity in vivo from indicator dilution curves. In Proc. Third IFAC Symposium on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 35-38, 1997.

  132. Cobelli C., Vicini P., Toffolo G., Caumo A.: The hot IVGTT minimal models: simultaneous assessment of disposal indices and endogenous glucose production. In The Minimal Model Approach and Determinants of Glucose Tolerance, R.N. Bergman and J.C. Lovejoy eds., Louisiana State University Press, Baton Rouge, Louisiana, 202-239, 1997.

  133. D’Angio’ L., Saccomani M.P., Audoly S., Bellu G., Cobelli C.: A new algorithm to test global identifiability of physiological nonlinear models. In Proc. IFAC Biomedical Symposium on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 259-264, 1997.

  134. Saccomani M.P., Audoly S., Bellu G., D’Angio’ L., Cobelli C.: Global identifiability of nonlinear model parameters. In Proc. of the SYSID ’97, 11th IFAC Symposium on Systems Identification, Yoshikazu Savaragi and Setsuo Sagara eds., Nichigen Co. Ltd., Kitakyushu, Japan, 1, 219-224, 1997.

  135. Saccomani M.P., Audoly S., D’Angio’ L., Cobelli C.: A new software tool to test global identifiability of linear compartmental models. In Proc. IFAC Biomedical Symposium on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 253-258, 1997.

  136. Seno D., Toffolo G., Cobelli C.: Identifiability of regional fluxes from steady state tracer experiments. In Proc. 3rd IFAC Symp. on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 243-246, 1997.

  137. Simeoni M., Caumo A., Rizza R., Cobelli C.: Modeling glucose control on endogenous glucose production in nonsteady state: necessity of direct and delayed signalling. In Proc. 19th Ann. Int. Conf. IEEE-EMBS, Jaeger R.J. and Agarwal G.C. eds., IEEE, New York, 2138-2141, 1997.

  138. Sparacino G., Cobelli C.: Deconvolution of physiological and pharmacokinetic data: comparison of algorithms on benchmark problems. In Proc. 3rd IFAC Symp. on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 153-155, 1997.

  139. Thomaseth K., Cobelli C.: Parameter Information Content during Model Identification Experiments. In Proc. 3rd IFAC Symposium on Modelling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 107-112, 1997.

  140. Toffolo G., Arduini A., De Zanche N., Avogaro A., Cobelli C.: A minimal model of insulin during insulin modified IVGTT: assessment of hepatic insulin extraction. In Proc. 3rd IFAC Symp. on Modeling and Control in Biomedical Systems, Linkens D.A. and Carson E. eds., Elsevier, Amsterdam, 91-95, 1997.

  141. Toffolo G., Cobelli C.: Protein fractional synthetic rate: theory and practice. In Amino Acid and Protein Metabolism in health and disease: nutritional implications, P.Tessari, P.B.Soeters, G.Pittoni, A.Tiengo eds., Smith Gordon-Nishimura, London, UK, 23-30, 1997.

  142. Toffolo G., Cobelli C.: Role of C-peptide kinetics in methods for assessing insulin secretion: lessons from a new minimal model. In The Minimal Model Approach and Determinants of Glucose Tolerance, R.N. Bergman and J.C.Lovejoy eds., Louisiana State University Press, Baton Rouge, Louisiana, 283-304, 1997.

  143. Nucci G., Polese G., Rossi A., Cobelli C.: On-line estimation of respiratory parameters of lung mechanics in different pathologies. In Proc. 19th Annual IEEE-EMBS Conference, Chicago (IL), pp. 2058-2060, 1997.

  144. Simeoni M., Caumo A., Rizza R., Cobelli C.: Modeling glucose control on endogenous glucose production in nonsteady state: necessity of direct and delayed signalling. In Proc. 19th Annual IEEE EMBS Conference in Medicine, Chicago IL, pp. 2138-41, 1997.

  145. Cobelli C., Bettini F., Caumo A, Quon M.J.: Overestimation of minimal model glucose effectiveness in presence of insulin response is due to undermodeling. Am. J. Physiol. 275: E1031-E1036, 1998.

  146. Cobelli C., Foster D.M.: Compartmental models: theory and practice using the SAAM II software system. Adv. Exp. Med. Biol. 445: 79-101, 1998.

  147. Dobbins R.L., Davis S.N., Neal D., Caumo A., Cobelli C., Cherrington A.D.: Rates of glucagon activation and deactivation of hepatic glucose production in conscious dogs. Metabolism 47: 135-142, 1998.

  148. Cobelli C., Nucci G., Del Prato S.: A physiological simulation model of the glucose-insulin system. In Proc. BMES/EMBS Conference, Atlanta, GA, Oct. 13-16, p. 999, 1999.

  149. Nucci G., Tessarin S., Cobelli C.: Time-domain analysis of lung mechanics in the ventilated patient. In Proc. BMES/EMBS Conf., Atlanta, GA, Oct. 13-16, p. 325, 1999.

  150. Konrad T., Vicini P., Zeuzem S., Toffolo G., Briem D., Lormann J., Herrmann G., Wittman D., Lenz T., Kusterer K., Teuber G., Cobelli C., Usadel K.H.: Interferon-a improves glucose tolerance in diabetic and non-diabetic patients with HCV-induced liver disease. Exp. Clin. End. Diabetes 107: 343-349, 1999.

  151. Breda E., Cavaghan M.K., Ehrmann D.A., Toffolo G., Polonsky K.S., Cobelli C.: Assessment of Insulin Secretion in Response to both Physiological and Non-Physiological Glucose Stimuli: Deconvolution Versus C-peptide Minimal Model. In: CD-ROM Proc. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 23-28, 2000.

  152. Callegari T., Caumo A., Cobelli C.: The Bayesian Two-Compartment Minimal Model of Glucose Kinetics during Standard IVGTT: SAAM II vs ADPT II Implementation. In: CD-ROM Proc. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 23-28, 2000.

  153. Cobelli C., Sparacino G., Caumo A., Saccomani M.P., Toffolo G.: Compartmental Models of Physiologic Systems. In: J. Bronzino (Editor), The Biomedical Engineering Handbook (2nd Edition), Boca Raton, FL, CRC Press & IEEE Press 2: 159(1-11), 2000.

  154. Magni P., Bellazzi R., Sparacino G., Cobelli C.: Almost-Blind Deconvolution for Input Estimation in Physiological Systems. In: CD-ROM Proc. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 23-38, 2000.

  155. Pillonetto G., Sparacino G., Cobelli C.: Reconstruction of non-stationary biological signals via stochastic deconvolution. In: CD-ROM Proc. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 23-38, 2000.

  156. Sparacino G., Pillonetto G., De Nicolao G., Cobelli C.: STODEC: an interactive program for stochastic deconvolution in physiological and pharmacokinetic systems. In: E. Carson and E. Salzsieder (Editors), Modelling and Control in Biomedical Systems 2000, IFAC Symposium, Karlsburg, Germany, Oxford, UK, Pergamon Press, pp. 303-308, 2000.

  157. Zamuner S., Bertoldo A., Bergstrom M., Iavarone L., Fasth K.J., Langstrom B., Bani M., Bye A., Cobelli C.: Modeling of drug-receptor interaction in the monkey brain: a PET pharmacokinetic study. In: CD-ROM Proc. World Congress on Medical Physics and Biomedical Engineering, Chicago, July 23-38, 2000.