BioImLab - Biomedical Imaging Laboratory

K. Al Rashah, N. Pritchard, C. Dehghani, A. Ruggeri, P. Guimaraes, A. Russell, R. Malik, N. Efron, K. Edwards. Corneal Nerve Migration Rate in a Healthy Control Population, Optom Vis Sci, doi:10.1097/OPX.0000000000001254, 2018.

N.S. Lagali, S. Allgeier, P. Guimaraes, R.A. Badian, A. Ruggeri, B. Kohler, T.P. Utheim, B. Peebo, M. Peterson, L.B. Dahlin, and O. Rolandsson. Wide-field corneal subbasal nerve plexus mosaics in age-controlled healthy and type 2 diabetes populations, Sci. Data, 5:180075, 2018.

N.S. Lagali, S. Allgeier, P. Guimaraes, R.A. Badian, A. Ruggeri, B. Kohler, T.P. Utheim, B. Peebo, M. Peterson, L.B. Dahlin, and O. Rolandsson. Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis, Invest Ophthalmol Vis Sci, 58(14):6318-27, Dec 2017.

W. Xiang, B. Reglin, B. Nitzsche, M. Maibier, W. Rong, B. Hoffmann, A. Ruggeri, P. Guimaraes, T.W. Secomb and A.R. Pries. Dynamic remodeling of arteriolar collaterals after acute occlusion in chick chorioallantoic membrane, Microcirculation, 24:e12351, https://doi.org/10.1111/micc.12351, 2017.

E. Pedrotti, F. Bosello, A. Fasolo, A.C. Frigo, I. Marchesoni, A. Ruggeri, G. Marchini. Transcutaneous periorbital electrical stimulation in the treatment of dry eye, Br J Ophthalmol, 101:814-9, 2017.

J. Wigdahl, P. Guimaraes, A. Ruggeri. A shortest path approach to optic disc detection in retinal fundus images, Journal for Modeling in Ophthalmology, 4:29-42, 2016.

K. Al Rashah, N. Pritchard, C. Dehghani, A. Ruggeri, P. Guimaraes, C. Poole, A. Russell, R. Malik, N. Efron, K. Edwards. Repeatability of Measuring Corneal Nerve Migration Rate in Individuals With and Without Diabetes, Cornea, 35(10):1355-1361, Oct 2016.

P. Guimaraes, J. Wigdahl, and A. Ruggeri. A Fast and Efficient Technique for the Automatic Tracing of Corneal Nerves in Confocal Microscopy, Trans Vis Sci Tech., 5(5):7, pp.1-9, Sep 2016.

J. Leckelt, P. Guimaraes, A. Kott, A. Ruggeri, O. Stachs, and S. Baltrusch. Early detection of diabetic neuropathy by investigating CNFL and IENFD in thy1-YFP 1 mice, Journal of Endocrinology, 231(2):147-157, 2016.

F. Scarpa, A. Ruggeri. Development of a reliable automated algorithm for the morphometric analysis of human corneal endothelium, Cornea, 35(9):1222-1228, Sep 2016.

L. Bonaldi, E. Menti, L. Ballerini, A. Ruggeri, E. Trucco. Automatic Generation of Synthetic Retinal Fundus Images: Vascular Network, Procedia Computer Science, 90:54-60, 2016.

M. Parissi, S. Randjelovic, E. Poletti, P. Guimaraes, A. Ruggeri, S. Fragkiskou, T.B. Wihlmark, T.P. Utheim, N. Lagali. Corneal Nerve Regeneration After Collagen Cross-Linking Treatment of Keratoconus. A 5-Year Longitudinal Study, JAMA Ophthalmol, 134(1):70-78, Jan 2016.

M. Reichard, H. Weiss, E. Poletti, A. Ruggeri, R.F. Guthoff, O. Stachs, and S. Baltrusch. Age-Related Changes in Murine Corneal Nerves, Current Eye Research, DOI: 10.3109/02713683.2015.1088952, Dec 2015.

N. Lagali, E. Poletti, D.V. Patel, C.N.J. McGhee, P. Hamrah, A. Kheirkhah, M. Tavakoli, I.N. Petropoulos, R.A. Malik, T.P. Utheim, A. Zhivov, O. Stachs, K. Falke, S. Peschel, R. Guthoff, C. Chao, B. Golebiowski, F. Stapleton, and A. Ruggeri. Focused Tortuosity Definitions Based on Expert Clinical Assessment of Corneal Subbasal Nerves, Invest Ophthalmol Vis Sci, 56(9):5102-9, Aug 2015.

J. Schroeter, A. Ruggeri, H. Thieme, C. Meltendorf. Impact of temporary hyperthermia on corneal endothelial cell survival during organ culture preservation, Graefes Arch Clin Exp Ophthalmol, 253(5):753-8, May 2015.

M. Parissi, G. Karanis, S. Randjelovic, J. Germundsson, E. Poletti, A. Ruggeri, T.P. Utheim, and N. Lagali. Standardized Baseline Human Corneal Subbasal Nerve Density for Clinical Investigations with Laser-scanning in Vivo Confocal Microscopy, Invest Ophthalmol Vis Sci , 54(10):7091-102, Oct 2013.

E. Trucco, A. Ruggeri, T. Karnowski, L. Giancardo, E. Chaum, J.P. Hubschman, B. al-Diri, C.Y. Cheung, D. Wong, M. Abramoff, G. Lim, D. Kumar, P. Burlina, N.M. Bressler, H.F. Jelinek, F. Meriaudeau, G. Quellec, T. MacGillivray, and B. Dhillon. Validating Retinal Fundus Image Analysis Algorithms: Issues and a Proposal, Invest Ophthalmol Vis Sci , 54(5):3446-59, May 2013.

E. Poletti, F. Zappelli, A. Ruggeri, E. Grisan. A Review of Thresholding Strategies Applied to Human Chromosome Segmentation, Comput Methods Programs Biomed, 108(2):679-88, Nov 2012.

E. Poletti, E. Grisan, A. Ruggeri. A Modular Framework for the Automatic Classification of Chromosomes in Q-Band Images, Comput Methods Programs Biomed, 105(2):120-30, Feb 2012.

F. Scarpa, X. Zheng, Y. Ohashi, A. Ruggeri. Automatic Evaluation of Corneal Nerve Tortuosity in Images from In-vivo Confocal Microscopy, Invest Ophthalmol Vis Sci , 52(9):6404-8, 2011.

L. Tramontan, E. Poletti, D. Fiorin, and A. Ruggeri. A web-based system for the quantitative and reproducible assessment of clinical indexes from the retinal vasculature, IEEE Trans Biomed Eng, 58(3):818-821, 2011.

L. Giancardo, F. Meriaudeau, T.P. Karnowski, K.W. Tobin, E. Grisan, P. Favaro, A. Ruggeri, and E. Chaum. Textureless macula swelling detection with multiple retinal fundus images, IEEE Trans Biomed Eng, 58(3):795-799, 2011.

X. Zheng, A. Shiraishi, S. Okuma, S. Mizoue, T. Goto, S. Kawasaki, T. Uno, T. Miyoshi, A. Ruggeri, and Y. Ohashi. In vivo confocal microscopic evidence of keratopathy in patients with pseudoexfoliation syndrome, Invest Ophthalmol Vis Sci, 52(3):1755-1761, 2011.

A. Ruggeri, F. Scarpa, M. De Luca, C. Meltendorf, J. Schroeter. A system for the automatic estimation of morphometric parameters of corneal endothelium in alizarine red stained images, Br J Ophthalmol, 94:643-7, 2010.

A. Bagno, F. Anzil, V, Tarzia, V. Pengo, A. Ruggeri, G. Gerosa. Application of wavelet analysis to the phonocardiographic signal of mechanical heart closing sounds, Int J Artif Organs, 32:166-172, 2009.

E. Grisan, E. Poletti, A. Ruggeri. Automatic segmentation and disentangling of chromosome in Q-band prometaphase images, IEEE Trans Inf Technol Biomed 13(4):575-81, Jul 2009.

F. Scarpa, E. Grisan, A. Ruggeri. Automatic recognition of corneal nerve structures in images from confocal microscopy. Invest Ophthalmol Vis Sci 49(11):4801-7, Nov 2008.
E. Grisan, M. Foracchia, A. Ruggeri. A novel method for the automatic grading of retinal vessel tortuosity. IEEE Trans Med Imag 27(3):310-9, Mar 2008.

G. Naletto, F. Frassetto, N. Codogno, E. Grisan, S. Bonora, V. Da Deppo, A. Ruggeri. No wavefront sensor adaptive optics system for compensation of primary aberrations by software analysis of a point source image. 2. Tests. Applied Optics 46(25):6427-33, Sep 2007.

E. Grisan, F. Frassetto, V. Da Deppo, G. Naletto, A. Ruggeri. No wavefront sensor adaptive optics system for compensation of primary aberrations by software analysis of a point source image. 1. Methods. Applied Optics 46(25):6434-41, Sep 2007.

A. Ruggeri, E. Grisan, J. Schroeter. Evaluation of repeatability for the automatic estimation of endothelial cell density in donor corneas. Br J Ophthalmol 91:1213-1215, Sep 2007.

F. Zulian, D. Meneghesso, E. Grisan, F. Vittadello, A. Belloni Fortina, B. Pigozzi, A. C. Frigo, G. Martini, A. Ruggeri. A new computerized method for the assessment of skin lesions in localized scleroderma. Rheumatology 46:856-860, May 2007.

M. Foracchia, E. Grisan, A. Ruggeri. Luminosity and contrast normalization in retinal images. Med Image Anal 9/3:179-190, 2005.

A. Ruggeri, E. Grisan, J. Jaroszewski. A new system for the automatic estimation of endothelial cell density in donor corneas. Br J Ophthalmol 89:306-311, Mar 2005.

M. Foracchia, E. Grisan, A. Ruggeri. Detection of optic disc in retinal images by means of a geometrical model of vessel structure. IEEE Trans Med Imag 23:1189-1195, 2004.

M. Foracchia, A. Ruggeri. Automatic estimation of endothelium cell density in donor corneas by means of Fourier analysis. Med Biol Eng Comput 42(5): 725-731, Sep 2004.

M. Foracchia, A. Hooker, P. Vicini, A. Ruggeri. POPED,a software for optimal experiment design in population kinetics. Comput Methods Programs Biomed 74:29-46, 2004.

A. Ruggeri, S. Pajaro. Automatic recognition of cell layers in corneal confocal microscopy images. Comput Methods Programs Biomed 68:25-35, 2002.

A. Ruggeri, G. Comai, M. Belloni, A. Zanella. A simulation study for the design of a control system based on artificial neural network for the blood concentration process in autotransfusion. Ann Biomed Eng 28:470-482, 2000.

A. Ruggeri, M. Martinelli. A program for the optimization of cyclosporine therapy using population kinetics modeling. Comput Methods Programs Biomed 61:61-69, 2000.

C. Macor, A. Ruggeri, P. Mazzonetto, G. Federspil, C. Cobelli, and R. Vettor. Visceral adipose tissue impairs insulin secretion and insulin sensitivity but not energy expenditure in obesity. Metabolism 46:123-129, 1997.

A. Ruggeri, F. Carmignoto, A.M.R. Matano. Development and evaluation of a knowledge based system to assess drug’s safety profile from laboratory data. Drug Information Journal 30:413-419, 1996.

R. Vettor, C. Macor, E. Rossi, C. De Palo, A. Ruggeri, C. Cobelli, G. Federspil. Effect of naltrexone treatment on insulin secretion, insulin action and postprandial thermogenesis in obesity. Horm Metab Res 26:188-194, 1994.

DO IT EASD Study Group. Guidelines to support the optimal implementation and use of information systems in diabetes care. Diab Nutr Metab 5:141-150, 1992.

C. Cobelli, A. Ruggeri. A reduced sampling schedule for estimating the parameters of the glucose minimal model from a labelled IVGTT. IEEE Trans Biomed Eng 38:1023-1029, 1991.

C. Cobelli, A. Ruggeri. Optimal design of sampling schedules for studying glucose kinetics with tracers. Am J Physiol 257:E444-E450,1989.

C. Cobelli, A. Ruggeri, J.J. DiStefano, III, E.M. Landaw. Optimal design of multioutput sampling schedules - Software and applications to endocrine-metabolic and pharmacokinetic models. IEEE Trans Biomed Eng 32:249-256, 1985.

C. Cobelli, A. Ruggeri, G. Toffolo, A. Avogaro and R. Nosadini. Is the "pool-fraction" paradigm a valid model for assessment of in vivo turnover in non-steady state? Am J Physiol 245:R624-R632, 1983 .

C. Cobelli and A. Ruggeri. Evaluation of portal/peripheral route and of algorithms for insulin delivery in the closed-loop control of glucose in diabetes - A modeling study. IEEE Trans Biomed Eng 30:93-103, 1983.

C. Cobelli, J.J. DiStefano, III, A. Ruggeri. Minimal sampling schedule for identification of dynamic models of metabolic systems of clinical interest: case studies for two liver function tests. Math Biosci 63:173-186, 1983.

C. Cobelli, A. Ruggeri. Evaluation of alternative model structures of metabolic systems. Two case studies on model identification and validation. Med Biol Eng Comput 20:444-450, 1982.

L. Okoliksanyi, R. Orlando, M. Venuti, G. Dal Brun, C. Cobelli, A. Ruggeri, A. Salvan. A modeling study of the effect of fasting on bilirubin kinetics in Gilbert's syndrome. Am J Physiol 240:R266-R271, 1981.

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Papers in italian journals

A. Ruggeri e C. Cobelli. Sistemi esperti in medicina. Wellcome Tabloid V-2:30-34,1993.

D. Ponzin e A. Ruggeri. Un atlante interattivo come ausilio alla valutazione delle cornee per trapianto. L'oculista italiano 132:35-37, 2002.

S. Vecchiato, A. Ruzza, P. Donisi e A. Ruggeri. Il microscopio ottico e la valutazione delle opacita' corneali. L'oculista italiano 134:18-21, 2002.

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Papers in international books or conference proceedings

C. Cobelli, A. Madonna and A. Ruggeri. Testing of model structures in identification of metabolic systems. Proc. 18th IEEE Conference on Decision and Control, Vol. 1, pp. 516-517, IEEE, New York, 1979.

C. Cobelli, A. Ruggeri, G. Toffolo, L. Okoliksanyi, M. Venuti and R. Orlando. BSP vs. bilirubin kinetics in Gilbert's syndrome. In Familial Hyperbilirubinemia, pp. 121-131, Wiley, Chichester (UK), 1981.

L. Okolicsanyi, R. Orlando, M. Venuti, C. Cobelli, A. Ruggeri and G. Pacini. Observations on the mechanism of fasting hyperbilirubinemia. In Familial Hyperbilirubinemia, pp. 147-155, Wiley, Chichester (UK), 1981.

C. Cobelli , G. Pacini, A. Ruggeri, S. Del Prato, E. Duner, R. Nosadini and A. Tiengo. Algorithms for closed-loop glucose control (artificial pancreas) in diabetes. A novel noninvasive approach for their comparative evaluation based on mathematical modeling. In Control Science And Technology For The Progress Of Society, pp. 3711-3716, IFAC Pergamon Press, Oxford (UK), 1981.

C. Cobelli and A. Ruggeri. Open loop insulin infusion systems in diabetes. A modeling study of intravenous delivery strategies. In MEDINFO83, Part 2, pp. 891-894, North-Holland, Amsterdam (The Netherlands), 1983.

C. Cobelli, J.J. DiStefano, III, A. Ruggeri. Optimal experiment design in clinical medicine: a computer program and applications to compartmental models. Proc. Eighth Annual Symposium on Computer Applications in Medical Care, pp. 132-135, IEEE, New York, 1984.

C. Cobelli and A. Ruggeri. Model-based parameter measurement from clinical tests. Reduction of number of blood samples via optimal sampling schedule design. Proc. XIV International Conference on Medical and Biological Engineering and VII International Conference on Medical Physics, Med & Biol Eng & Comput, 23 supplement part 1: 364-365, 1985.

C. Cobelli, A. Ruggeri, K. Thomaseth. Optimal input and sampling schedule for physiological system identification. Some theoretical and in vivo results on a compartmental model of glucose kinetics. In Mathematics and Computers in Biomedical Applications, pp. 161-172, Elsevier North-Holland, New York, 1985.

A. Ruggeri, C. Cobelli. Optimal sampling schedule design may reveal inadequacy of model structure: a case study on the minimal model of glucose disappearance. In Modelling and Control in Biomedical Systems, pp. 121-125, IFAC Pergamon Press, Oxford (UK), 1989.

A. Ruggeri, C. Cobelli, M. Mussap, L. Nemetz, M. Plebani, M. Zaninotto and A. Burlina. Evaluation of an expert system in laboratory medicine. Proc. V Mediterranean Conference on Medical & Biological Engineering "MEDICON 89", pp. 274-275, University of Patras, Patras (Greece), 1989.

A. Ruggeri, C. Cobelli, G. Toffolo and G. Hetenyi. A time-varying compartmental model to assess non-steady state glucose kinetics in hypoglycemia from tracer data. In Images of the Twenty First Century - Proc.11th Annual International Conference of the IEEE- EMBS, Part 1/6, pp. 258-259, IEEE, New York, 1989.

A. Ruggeri, C. Cobelli. A reduced sampling schedule for identifying model-based parameters of glucose metabolism: design and validation. In MEDINFO 89, Part 1, pp. 533-537, North-Holland, Amsterdam (The Netherlands), 1989.

A. Ruggeri, C. Cobelli, A. Caumo and G. Hetenyi. Estimation of non-steady state hepatic glucose production by deconvolution with a time-varying compartmental model. In Biomedical Engineering Perspectives: Health Care Technologies for the 1990's and Beyond - Proc. 12th Annual International Conference of the IEEE- EMBS, Part 3/5, pp.1000-1001, IEEE, New York, 1990.

A. Ruggeri. Towards a minimal number of informative samples for model based parameter measurement in biomedical systems. Proc. 6th IMEKO Conference on Measurement in Clinical Medicine, pp. 119-121, Scientific Society of Measurement and Automation, Budapest (Hungary), 1990.

A. Ruggeri and C. Cobelli. The minimal model of glucose disappearance: relaxing the error-free insulin input assumption. In New Frontiers of Biomedical Engineering - Proc. 13th Annual International Conference of the IEEE-EMBS, Part 5/5, pp. 2287-2288, IEEE, New York, 1991.

G.P. Reboldi, A. Ruggeri, G. Quintaliani, U. Buoncristiani, A. Bueti, F. Santeusanio, C. Cobelli , P. Brunetti. Effect of different immunosuppressive regimens on glucose tolerance and insulin secretion in non diabetic kidney transplanted patients. In Current topics in Diabetes Research. Frontiers in Diabetes, vol. 12, pp. 267-271, Karger, Basel (CH), 1993.

D.M. Foster, P.H. Barrett, W.F. Beltz, C. Cobelli, H. Golde, J.A. Jacquez, R.D. Phair, A. Ruggeri, M.P. Saccomani, D.M. Shames, G. Toffolo. SAAMII: a reengineered, menu-driven SAAM for enhancing biokinetic applications. In Simulation in Health Sciences and Services, pp. 109-114, The Society for Computer Simulation, San Diego (CA), USA, 1993.

A. Ruggeri, F. Carmignoto and A.M.R. Matano. LABIESS, an expert system for laboratory data to assess drug safety profile. In Engineering Solutions to Current Health Care Problems - Proc. 15th Annual International Conference of the IEEE-EMBS, Part 2/3, pp. 630-631, IEEE, New York, 1993.

D.M. Foster, P.H. Barrett, B.M. Bell, W.F. Beltz, C. Cobelli, H. Golde, J.A. Jacquez, R.D. Phair, A. Ruggeri, M.P. Saccomani, A. Schumitzky, G. Toffolo. Using SAAM-II to model kinetic and pharmacokinetic data. Proc. Simulation in Health Sciences Conferences, pp. 87-90, Society for Computer Simulation, San Diego (CA), USA, 1994.

A. Ruggeri and C. Cobelli. Role of insulin error on minimal model parameter estimates in various IVGTT protocols. In Modeling and Control in Biomedical Systems, pp. 283-284, Proc. IFAC Symposium, Galveston (TX), USA, 1994.

A. Ruggeri, G. Danzi. Artificial neural networks for the classification of electrophoretic patterns. In Basic & Applied Biomedical Engineering - Building Blocks for Health Care - Proc. 17th Annual International Conference of the IEEE-EMBS, pp. 825-826, IEEE, New York, 1995.

A. Ruggeri. A new program for the design of optimal sampling schedules in dynamic experiments for model identification. In Model Based Biomeasurements - Proc. 7th International IMEKO TC-13 Conference, pp. 33-36, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, 1995.

A. Ruggeri, S. Giove, M. Nordio. Models of phosphate kinetics in dialysis patients. In Bridging Disciplines for Biomedicine - Proc. 18th Annual International Conference of the IEEE-EMBS, IEEE, New York, 1996.

A. Ruggeri, A. Logiudice, W. Rainer, A. Erlicher. A new approach for a minimally invasive measurement of cardiac contractility via ventricle elastance. In Magnificent Milestones and Emerging Opportunities in Medical Engineering - Proc. 19th Annual International Conference of the IEEE-EMBS, pp. 248-250, IEEE, New York, 1997.

A. Ruggeri, S. Giove, M. Nordio. New models of phosphate kinetics in dialysis patients. In Magnificent Milestones and Emerging Opportunities in Medical Engineering - Proc. 19th Annual International Conference of the IEEE-EMBS, pp. 2132-2135, IEEE, New York, 1997.

A. Ruggeri, M. Nordio, S. Giove. A simulation model of water volume and sodium kinetics during dialysis. In EMBEC '99 - Proc. European Medical and Biological Engineering Conference , pp. 1158-1159, Med. Biol. Eng. Comput., 37 (supplement 2):1158-59, 1999.

M. Foracchia, A. Ruggeri. Cell contour detection in corneal endothelium in-vivo microscopy. Proc. Chicago 2000 - World Congress on Medical Physics and Biomedical Engineering, pp. 1033-1035, IEEE, New York, 2000.

A. Ruggeri, S. Pajaro, A. Vita. Classification of corneal layers in confocal microscopy. Proc. Chicago 2000 - World Congress on Medical Physics and Biomedical Engineering, pp. 1030-1032, IEEE, New York, 2000.

R. Speller, A. Ruggeri, The CDA recommendations. In Towards a European Framework for Education and Training in Medical Physics and Biomedical Engineering (Z. Kolitsi, Ed.), pp. 89-113, IOS Press, Amsterdam (The Netherlands), 2001.

M. Foracchia, A. Ruggeri. Estimating cell density in corneal endothelium by means of Fourier analysis. Proc. 2nd Joint IEEE-EMBS/BMSE Conference, pp. 1097-98, IEEE, New York, 2002.

A. Ruggeri, M. Foracchia, E. Grisan. A computerized system for the measurement of transit times in dynamic fluoroangiography. EMBEC'02 - IFMBE Proc. Series Vol. 3, pp. 1556-57, IFMBE, 2002.

M. Foracchia, E. Grisan, A. Ruggeri. Detection of vessel caliber irregularities in color retinal fundus images by means of fine tracking. EMBEC'02 - IFMBE Proc. Series Vol. 3, pp. 1558-59, IFMBE, 2002.

M. Foracchia, A. Ruggeri. Corneal endothelium analysis by means of Bayesian shape modeling. Proc. 25th Annual International Conference of the IEEE-EMBS, pp. 794-797, IEEE, New York, 2003.

E. Grisan, M. Foracchia and A. Ruggeri. A novel method for the automatic evaluation of retinal vessel tortuosity. Proc. 25th Annual International Conference of IEEE-EMBS, pp. 866-869, IEEE, New York, 2003.

E. Grisan and A. Ruggeri. A divide et impera strategy for automatic classification of retinal vessels into arteries and veins. Proc. 25th Annual International Conference of IEEE-EMBS, pp. 890-894, IEEE, New York, 2003.

A. Ruggeri, M. Foracchia, E. Grisan. Detecting the optic disc in retinal images by means of a geometrical model of vessel network. Proc. 25th Annual International Conference of IEEE-EMBS, pp. 902-905, IEEE, New York, 2003.

M. Visentin, A. Ruggeri, and A. Bezerianos. Analysis of cardiac MRI images with active contour model and wavelet decomposition. Proc. 4th Symposium on Biomedical Engineering, University of Patras, Patras (Greece), 2004 (CD-ROM).

E. Grisan, A. Pesce, A. Giani, M. Foracchia, and A. Ruggeri. A new tracking system for the robust extraction of retinal vessel structure. Proc. 26th Annual International Conference of IEEE-EMBS, pp. 1620-1623, IEEE, New York, 2004.

E. Grisan, A. Paviotti, N. Laurenti, and A. Ruggeri. A lattice estimation approach for the automatic evaluation of corneal endothelium density. Proc. 27th Annual International Conference of IEEE-EMBS, pp. 1700-1703, IEEE, New York, 2005.

E. Grisan, F. Frassetto, V. Da Deppo, G. Naletto, and A. Ruggeri. Aberration estimation from single point image in a simulated adaptive optics system. Proc. 27th Annual International Conference of IEEE-EMBS, pp. 3173-3176, IEEE, New York, 2005.

A. Giani, E. Grisan, and A. Ruggeri. Enhanced classification-based vessel tracking using vessel models and Hough transform. EMBEC'05 - IFMBE Proc. Series, Vol. 11, IFMBE, 2005 (CD-ROM).

E. Grisan, and A. Ruggeri. A hierarchical Bayesian classification for non-vascular lesions detection in fundus images. EMBEC'05 - IFMBE Proc. Series, Vol. 11, IFMBE, 2005 (CD-ROM).

E. Grisan, A. Giani, E. Ceseracciu, A. Ruggeri. Model-based illumination correction in retinal images. Proc. IEEE International Symposium on Biomedical Images, pp. 984-7, IEEE, New York, 2006.

A. Giani, E. Grisan, M. De Luca, A. Ruggeri. Detecting false vessel recognitions in retinal fundus analysis. Proc. 28th Annual International Conference of IEEE-EMBS, pp. 4449-52, IEEE, New York, 2006.

A. Ruggeri, F. Scarpa, E. Grisan. Automatic Tracing of Subbasal Nerves in Confocal Microscopy Images. Proc. 28th Annual International Conference of IEEE-EMBS, pp. 4739-42, IEEE, New York, 2006.

F. Scarpa, D. Fiorin, and A. Ruggeri. In Vivo Three-Dimensional Reconstruction of the Cornea from Confocal Microscopy Images. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 747-50, IEEE, New York, 2007.

M. Martinello, P. Favaro, G. D. Muyo Nieto, A. R. Harvey, E. Grisan, F. Scarpa, and A. Ruggeri. 3-D Retinal Surface Inference: Stereo or Monocular Fundus Camera? Proc. 29th Annual International Conference of IEEE-EMBS, pp. 896-9, IEEE, New York, 2007.

E. Grisan, E. Poletti, C. Tomelleri, and A. Ruggeri. Automatic segmentation of chromosomes in Q-band images. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 5513-6, IEEE, New York, 2007.

M. Foracchia and A. Ruggeri. Corneal Endothelium Cell Field Analysis by means of Interacting Bayesian Shape Models. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 6035-8, IEEE, New York, 2007.

A. Ruggeri, E. Grisan, M. De Luca. An automatic system for the estimation of generalized arteriolar narrowing in retinal images. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 6463-6, IEEE, New York, 2007.

E. Grisan and A. Ruggeri. Segmentation of candidate dark lesions in fundus images based on local thresholding and pixel density. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 6735-8, IEEE, New York, 2007.
A. Bagno, R. Buselli, F. Anzil, V. Tarzia, V. Pengo, A. Ruggeri, T. Bottio, G. Gerosa. In vitro characterization of bileaflet mnechanical heart valves closing sound. Proc. Computers on Cardiology 35, pp. 945-7, 2008.

E. Poletti, E. Grisan and A. Ruggeri. Automatic classification of chromosomes in Q-band images. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 1911-4, IEEE, New York, 2008.

L. Tramontan, E. Grisan and A. Ruggeri. An improved system for the automatic estimation of the Arteriolar- to-Venular diameter Ratio (AVR) in retinal images. Proc. 29th Annual International Conference of IEEE-EMBS, pp. 3550-3, IEEE, New York, 2008.
E. Grisan and A. Ruggeri. A Markov Random Field Approach to Outline Lesions in Fundus Images. ECIFMBE 2008, IFMBE Proceedings 22, pp. 472–5, Springer-Verlag, Berlin Heidelberg 2008.
E. Grisan, A. Tiso and A. Ruggeri. Estimation of Real-Time Red Blood Cell Velocity in Conjunctival Vessels using a Modified Dynamic-Time-Warping Approach. ECIFMBE 2008, IFMBE Proceedings 22, pp. 480–3, Springer-Verlag, Berlin Heidelberg 2008.

E. Grisan, A. Tiso, A. Ruggeri. Dynamic Time Warping and Cross Correlation for the estimation of cell movements in conjunctival capillaries: a comparison through simulation. WC 2009, IFMBE Proceedings 25/XI, pp. 112–5, Springer-Verlag, Berlin Heidelberg 2009.

E. Poletti, D. Fiorin, E. Grisan and A. Ruggeri. Retinal Vessel Axis Estimation through a Multi-Directional Graph Search Approach. WC 2009, IFMBE Proceedings 25/XI, pp. 137–40, Springer-Verlag, Berlin Heidelberg 2009.

L. Tramontan and A. Ruggeri. Computer estimation of the AVR parameter in diabetic retinopathy. WC 2009, IFMBE Proceedings 25/XI, pp. 141–44, Springer-Verlag, Berlin Heidelberg 2009.

D. Fiorin, E. Poletti, E. Grisan and A. Ruggeri. Fast adaptive axis-based segmentation of retinal vessels through matched filters. WC 2009, IFMBE Proceedings 25/XI, pp. 145–8, Springer-Verlag, Berlin Heidelberg 2009.

E. Grisan, E. Poletti, A. Ruggeri. An Improved Segmentation of Chromosomes in Q-Band Prometaphase Images Using a Region Based Level Set. WC 2009, IFMBE Proceedings 25/XI, pp. 748–51, Springer-Verlag, Berlin Heidelberg 2009.

P. Kasae, A. Ruggeri. Automated detection of hard exudates in retinal images. WOC 2010 Proceedings, pp. P-MO-269, 2010.

A. Ruggeri, G. Ughi, E. Grisan, T. Peto. Automated estimation of image-level vessel tortuosity in retinal images. WOC 2010 Proceedings, pp. SU-62-01, 2010.

D.Fiorin, A. Ruggeri. Computerized Analysis of Narrow-field ROP Imagesfor the Assessment of Vessel Caliber and Tortuosity, Proc. 33rd Annual International Conference of IEEE-EMBS, pp. 2622-5, IEEE, New York, 2011.

A. Ruggeri, E. Poletti, D. Fiorin, L. Tramontan. From Laboratory to Clinic: the Development of Web-based Tools for the Estimation of Retinal Diagnostic Parameters, Proc. 33rd Annual International Conference of IEEE-EMBS, pp. 3379-82, IEEE, New York, 2011.

E. Poletti, D. Fiorin, E. Grisan, A. Ruggeri. Automatic Vessel Segmentation in Wide-field Retina Images of Infants with Retinopathy of Prematurity, Proc. 33rd Annual International Conference of IEEE-EMBS, pp. 3954-7, IEEE, New York, 2011.

E. Poletti, A. Ruggeri, E. Grisan. An Improved Classification Scheme for Chromosomes with Missing Data, Proc. 33rd Annual International Conference of IEEE-EMBS, pp. 5072-5, IEEE, New York, 2011.

E. Poletti, E. Grisan, A. Ruggeri. Image-level Tortuosity Estimation in Wide-field Retinal Images from Infants with Retinopathy of Prematurity, Proc. 34th Annual International Conference of IEEE-EMBS, pp. 4958-61, IEEE, New York, 2012.

E. Poletti, A. Ruggeri. Segmentation of Vessels through Supervised Classification in Wide-field Retina Images of Infants with Retinopathy of Prematurity, Proc. 25th International Symposium on Computer-Based Medical System, pp. 1-6, IEEE, New York, 2012.

L. Tramontan, A. Ruggeri. Automatic Refinement of Vascular Tracking in Retinal Images: False Vessels Detection, Proc. 25th International Symposium on Computer-Based Medical System, pp. 1-6, IEEE, New York, 2012.

E. Poletti, A. Ruggeri. Automatic Nerve Tracking in Confocal Images of Corneal Subbasal Epithelium, Proc. 26th International Symposium on Computer-Based Medical System, pp. 119-24, IEEE, New York, 2013.

E. Poletti, G. Benedetti, A. Ruggeri. Super-Image Mosaic of Infant Retinal Fundus: Selection and Registration of the Best-quality Frames from Videos, Proc. 35th Annual International Conference of IEEE-EMBS, pp. 5883-6, IEEE, New York, 2013.

E. Trucco, A. Ruggeri. Towards A Multi-Site International Public Dataset For The Validation Of Retinal Image Analysis Software, Proc. 35th Annual International Conference of IEEE-EMBS, pp. 7152-5, IEEE, New York, 2013.

E. Poletti, A. Ruggeri. Segmentation of Corneal Endothelial Cells Contour through Classification of Individual Component Signatures, Proc. MEDICON 2013 IFMBE Proceedings 41, pp. 411-4, Springer International Publishing, Switzerland, 2013.

S. Fiorini, L. Ballerini, E. Trucco, A. Ruggeri. Automatic Generation of Synthetic Retinal Fundus Images, Proc. 18th MIUA Medical Image Understanding and Analysis,, pp. 7-12, BMVA, London, 2014.

J. Wigdahl, P. Guimaraes, E. Poletti, A. Ruggeri. Automatic detection of microdots in the stromal layer of corneal images, Proc. 36th Annual International Conference of IEEE-EMBS, pp. 210-3, IEEE, New York, 2014.

P. Guimaraes, J. Wigdahl, E. Poletti, A. Ruggeri. A fully-automatic fast segmentation of the sub-basal layer nerves in corneal images, Proc. 36th Annual International Conference of IEEE-EMBS, pp. 5422-5, IEEE, New York, 2014.

E. Poletti, J. Wigdahl, P. Guimaraes, A. Ruggeri. Automatic Montaging of Corneal Sub-Basal Nerve Images for the Composition of a Wide-Range Mosaic, Proc. 36th Annual International Conference of IEEE-EMBS, pp. 5426-9, IEEE, New York, 2014.

E. Poletti, A. Ruggeri. Graph Search Retinal Vessel Tracking, in Ophthalmological Imaging and Applications, pp. 97-114, CRC Press, Boca Raton (FL), USA, 2014.

S. Fiorini, L. Ballerini, E. Trucco, A. Ruggeri. Automatic Generation of Synthetic Retinal Fundus Images, Proc. MIUA 2014, 2014.

P. Guimaraes, W. Xiang, J. Wigdahl, B. Reglin, A. Pries, and A. Ruggeri. Measuring blood flow velocity from intravital video recordings, Proc. 37th Annual International Conference of IEEE-EMBS, pp. 6289-92, IEEE, New York, 2015.

G. Leontidis, J. Wigdahl, B. Al-Diri, A. Ruggeri, and A. Hunter. Evaluating Tortuosity in Retinal Fundus Images of Diabetic Patients Who Progressed to Diabetic Retinopathy, Proc. 37th Annual International Conference of IEEE-EMBS, IEEE, New York, 2015.

A. Scarpa and A. Ruggeri. Automatic Segmentation of Corneal Endothelial Cells Contours, Proc. 37th Annual International Conference of IEEE-EMBS, IEEE, New York, 2015.

J. Wigdahl, P. Guimaraes, G. Leontidis, A. Triantafyllou, and A. Ruggeri. Automatic Gunn and Salus Sign Quantification in Retinal Images, Proc. 37th Annual International Conference of IEEE-EMBS, pp. 5251-4, IEEE, New York, 2015.

F. Scarpa and A. Ruggeri. Segmentation of Corneal Endothelial Cells Contour by Means of a Genetic Algorithm, Proc. MICCAI-OMIA 2015, pp. 25-32, Iowa Research Online, Iowa City, 2015.

P. Guimaraes, J. Wigdahl, and A. Ruggeri. Automatic estimation of corneal nerves focused tortuosities, Proc. 38th Annual International Conference of IEEE-EMBS, pp. 1332-5, IEEE, New York, 2016.

A. Scarpa and A. Ruggeri. Automated Morphometric Description of Human Corneal Endothelium from in-vivo Specular and Confocal Microscopy, Proc. 38th Annual International Conference of IEEE-EMBS, pp. 1296-9, IEEE, New York, 2016.

F. Scarpa, C. Dalla Gassa, A. Ruggeri. Automated Morphometric Analysis of in-vivo Human Corneal Endothelium, Proc. MICCAI-OMIA 2016, pp. 89-96, Iowa Research Online, Iowa City, 2016.

F. Scarpa, A. Ruggeri. Development of Clinically Based Corneal Nerves Tortuosity Indexes, Proc. MICCAI-OMIA 2017, pp. 219-226, M.J. Cardoso et al. (Eds .): FIFI/OMIA 2017, LNCS 10554, 2017.

Papers in italian books or conference proceedings

C. Cobelli, G. Pacini, A. Ruggeri, S. Del Prato, R. Nosadini e A. Tiengo. Valutazione comparativa di alcuni algoritmi di controllo per pancreas artificiale. Atti della LXXXI Riunione Annuale AEI, I.53, pp.1-6, Associazione Elettrotecnica Italiana, Trieste, 1980.

C. Cobelli, A. Ruggeri, A. Burlina. Ausili informatici nell'interpretazione dei dati di laboratorio: modelli matematici e sistemi esperti. In Progressi in patologia clinica, pp. 117-127, Piccin, Padova, 1988.

A. Ruggeri, C. Cobelli, M. Mussap, L. Nemetz, M. Plebani e A. Burlina. Valutazione di un sistema esperto per la interpretazione di tracciati elettroforetici in medicina di laboratorio. In AIIM '89 - Atti del Congresso Nazionale 1989 dell'Associazione Italiana di Informatica Medica, pp. 318-323, Franco Angeli, Milano, 1989.

F. Beltrame, A. Cambiaso, C. Cobelli, M. Grattarola, G. Marcenaro, S. Martinoia, G. Rizzo, A. Ruggeri, G. Toffolo. Bioimmagini e strutture nervose: dal livello cellulare al livello d'organo. In Neuroscienze e scienze dell'artificiale: dal neurone all'intelligenza, pp. 87-112, Patron, Bologna, 1991.

P. Mazzonetto, S. Favro, E. Rossi, G. Ricciardi, F. Mangano, A. Ruggeri, C. Cobelli, R. Vettor. Relazioni tra distribuzione del tessuto adiposo addominale, sensibilita' insulinica e termogenesi postprandiale nel soggetto obeso. In Obesita' '92, p. 152-158, Edizioni Luigi Pozzi, Verona, 1992.

A. Ruggeri, F. Baldo. Informatica e telematica. In Medicina di Laboratorio - Principi di tecnologia, p 1447-1503, C.G. Edizioni Medico Scientifiche, Torino, 1994.

A. Ruggeri. Il progetto del campionamento ottimo: il software OSSMIMO. In Bioingegneria dei sistemi metabolici, pp. 285-290, Patron Editore, Bologna, 1998.

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Abstracts in international conference proceedings

C. Cobelli, A. Ruggeri, G. Toffolo, L. Okolicsanyi, R. Orlando and M. Venuti. An evaluation of the ability of the bilirubin and bromosulphthalein tests in discriminating patients with unconjugated hyperbilirubinemia. Proc. 6th BES "Over the water" Meeting on Biomedical Data Analysis and Modeling, Genova (Italy), Sept. 10-14 1979, p. 53, 1979.

C. Cobelli, A. Ruggeri and L. Okolicsanyi. Optimal design of the sampling schedule in dynamic experiments. An application to liver function test. Preprints Symposium on Mathematical Modelling of Metabolic and Endocrine Systems, Guilford (UK), Jul. 9-11 1980, p. 158, The Institute of Measurement and Control, London, 1980.

C. Cobelli, G. Pacini, A. Ruggeri, R. Nosadini, A. Tiengo. A comparative evaluation of different algorithms for external glucose control. A simulation study via a mathematical model (MM) of glucose regulation. Proc. Symposium on Islet-Pancreas Transplantation and Artificial Pancreas, Vouliagmeni Beach (Greece), Sept. 22-23 1980, p. 43, 1980.

S. Del Prato, A. Ruggeri, P. Tessari, P. Moghetti, R. Manunta, E. Duner, A. Avogaro and D. Fedele. Reduced Insulin Sensitivity (IS) in Type I Diabetics (D). Proc. American Diabetes Association Ann. Meet., Cincinnati, OH (USA), Jun. 14-16 1981, Diabetes, 30 suppl. 1: 83A, 1981 .

C. Cobelli, S. Del Prato, G. Pacini, A. Ruggeri and A. Tiengo. Evaluation of portal vs. peripheral route of insulin delivery for three artificial pancreas algorithms. Proc. International Symposium on Artificial Systems for Insulin Delivery, Assisi, Italy, Sept. 20-23 1981, p.29, University of Perugia, Perugia (Italy), 1981.

C. Cobelli, A. Mari and A. Ruggeri. A model of the comprehensive type may assist the solution of clinical problems related to closed-loop glucose control systems. Preprints Symposium on Control Systems Concepts and Approaches in Clinical Medicine, University of Sussex (UK), Apr. 5-7 1982, pp. 100-102, The Institute of Measurement and Control, London (UK), 1982.

C. Cobelli, R. Nosadini, A. Ruggeri and G. Toffolo Glucose and Ketone Body Turnover in the Non-Steady-State in Man: Is the Current Pool-Fraction Approach Reliable? Proc. EASD 18th Ann. Meet., Budapest (Hungary), Sept. 1-4 1982, Diabetologia, 23 : 161, 1982.

S. Del Prato, R. Nosadini, P. Moghetti, M.C. Marescotti, A. Ruggeri, C. Cobelli, M. Muggeo and A. Tiengo. Reduced Peripheral Glucose Disposal in Type I (Insulin-Dependent) Diabetes. Proc. EASD 18th Ann. Meet., Budapest (Hungary), Sept. 1-4 1982, Diabetologia, 23 : 163, 1982.

M. Muraca, M. Strazzabosco, R. Orlando, G. De Franchis, A. Ruggeri, C. Cobelli and L. Okolicsanyi. A simplified procedure for the determination of bilirubin kinetics in humans as a test for diagnosis of Gilbert syndrome. Proc. International Symposium on Assessment and Management of Hepatobiliary Disease, Padova (Italy), May 29-31 1986 .

M. Plebani, A. Ruggeri, L. Nemetz, M. Mussap, C. Cobelli, A. Burlina. Evaluation of an expert system for the interpretation of serum protein pattern. Proc. XIV International Congress of Clinical Chemistry, San Francisco, CA (USA), July 22-26 1990, Clinical Chemistry, 36: 1011, 1990.

G.P. Reboldi, A. Ruggeri, G. Quintaliani, R. Brugnano, M. Cozzari, U. Buoncristiani, A. Bueti, F. Santeusanio, M. Massi Benedetti, P. Brunetti, C. Cobelli. Cyclosporine induces a defect in insulin independent and dependent glucose disposal in kidney-transplanted patients: a minimal model assessment. Proc. 27th EASD Ann. Meet., Dublin (Ireland), Sept. 11-14 1991, Diabetologia, 34 suppl. 1: A76, 1991.

F. Saggiani, E. Bonora, M. Zenere, M.G. Artioli. A. Ruggeri, C. Cobelli and M. Muggeo. Insulin sensitivity, glucose sensitivity, b-cell secretion and insulin metabolism in human obesity. Proc. 27th EASD Ann. Meet., Dublin (Ireland), Sept. 11-14 1991, Diabetologia, 34 suppl. 1: A94, 1991.

G.P. Reboldi, G. Quintaliani, A. Ruggeri, H. Kulurianu, U. Buoncristiani, F. Santeusanio, P. Brunetti and C. Cobelli. Quantitative analysis of insulin sensitivity and secretion in kidney transplanted patients: a minimal model approach. Proc. 25th Ann. Meet. Americal Society of Nephrology, Washington (USA), Nov. 15-18, 1992, Journal of the Americal Society of Nephrology, 3: 876, 1992.

C. Martini, R. Vettor, C. Macor, C. De Palo, N. Sicolo, A. Ruggeri, C. Cobelli, G. Federspil. Studies on insulin secretion and glucose metabolism in acromegaly. Proc. 9th International Congress of Endocrinology, Nice (F), Aug. 30-Sept. 5, 1992, p. 358, 1993.

C. Macor, R. Vettor, E. Rossi, S. Favro, A.M. Lombardi, A. Ruggeri, C. Cobelli, G. Federspil. Study on insulin secretion and peripheral glucose metabolism by minimal model approach in obese subjects. Proc. 6th European Symposium on Metabolism, Padova, May 24-26, 1993, p. 62, 1993.

R. Vettor, C. Macor, E. Rossi, P. Mazzonetto, A. Ruggeri, C. Cobelli, G. Federspil. Influence of abdominal fat distribution on insulin secretion, insulin sensitivity and postprandial thermogenesis in obesity. Proc. 5th European Congress on Obesity, Ulm (D), June 10-12, 1993, Int. J. Obesity, p. 60, 1993.

A. Ruggeri and C. Cobelli. Accuracy and precision of minimal model indexes S_G and S_I in labelled IVGTT protocol. Proc. 3rd International Symposium on Minimal Modeling, Baton Rouge (LA), USA, June 9-10, 1994.

A. Ruggeri, P. Vicini, D. Foster, C. Cobelli. The minimal model of glucose disappearance available in SAAM II biomedical software. Proc. 3rd International Symposium on Minimal Modeling, Baton Rouge (LA), USA, June 9-10, 1994.

C. Macor, E. Bonora, R. Vettor, A. Ruggeri, M. Muggeo, G. Federspil and C. Cobelli. Glucose effectiveness in addition to insulin sensitivity is reduced in obese patients. Proc. 31th EASD Ann. Meet., Stockholm (Sweden), Sept. 12-16, 1995, Diabetologia, 38 suppl.1: A159, 1995.

G. Reboldi, G. Quintaliani, A. Ruggeri, G. Ciao, R.Errico, G. Toraldo, A. Bueti, U. Buoncristiani. Quantitative analysis of the short-term effect of two dialysis schedules on insulin sensitivity. Wiener Klinische Wochenschrift, 110 Jahrgang, Supplementum 4, p. 38, 1998.

A. Ruggeri, M. Foracchia. Automatic detection of cell contour in images of corneal endothelium from confocal microscopy. Proc. XIV International Conference of Eye Research, Santa Fe (NM), USA, Oct 15-20, 2000.

M. Foracchia, E. Grisan and A. Ruggeri. Extraction and quantitative description of vessel features in hypertensive retinopathy fundus images.Proc. 2^nd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA-2), Copenhagen, Denmark, Oct 5-7, 2001, nr. 6, p. 14, 2001.

A. Ruggeri, M. Foracchia. Quantitative analysis of transit times in dynamic fluoroangiography images. Proc. 2^nd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA-2), Copenhagen, Denmark, Oct 5-7, 2001, nr. 13, p. 18, 2001.

S. Piermarocchi, G. Lo Giudice, M. Sartore, A. Ruggeri. Quantitative angiographic measurement of the filling pre-injection time of the central retinal vein (CRV) in patients with glaucoma. Proc. 2^nd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA-2), Copenhagen, Denmark, Oct 5-7, 2001, nr. 14, p. 18, 2001.

E. Grisan, M. Foracchia and A. Ruggeri. Detection and classification of nonvascular diagnostic signs in retinopathy fundus images. Proc. 2^nd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA-2), Copenhagen, Denmark, Oct 5-7, 2001, nr. 19, p. 21, 2001.

D. Ponzin, M. Foracchia, D. Camposampiero, G. Barbaro and A. Ruggeri. Automatic determination of endothelial cell density in light microscopy. Proc. 14^th Annual Meeting European Eye Bank Association, Paris, France, Jan 18-19, 2002, p. 28, 2002.

A. Ruggeri, M. Foracchia, E. Grisan. Detection of optic disc based on a directional model of vascular network. Proc. 3^rd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA3), Eur. J. Ophthalmol. 13 (2): 228, 2003.

E. Grisan, M. Foracchia and A. Ruggeri. Normalization of luminance and contrast in fundus images. Proc. 3^rd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA3), Eur. J. Ophthalmol. 13 (2): 228, 2003.

M. Foracchia, E. Grisan and A. Ruggeri. Refinement of vessel caliber information from tracking algorithms by means of fine tracking. Proc. 3^rd International Workshop on Computer Assisted Fundus Image Analysis (CAFIA3), Eur. J. Ophthalmol. 13 (2): 229, 2003.

J. Jaroszewski, R. Rieger, P. Rieck, C. Hartmann, E. Grisan, A. Ruggeri. Computerized endothelial cell density calculation in the cornea bank. Graefes Arch Clin Exp Ophthalmol 241 (Suppl. 1): DO.07.06, 2003.

A. Ruggeri, E. Grisan, M. Foracchia. A model of the retinal vessel network as a tool to detect the position of optic disc in fundus images. Proc. MEDINF'2003, Craiova, Romania, Oct 9-11, 2003, p. 91-92, 2003.

A. Ruggeri, E. Grisan, J. Jaroszewski. A software system for the reliable automatic estimation of endothelial cell density. Proc. 16th Annual Meeting European Eye Bank Association, Barcelona, Spain, Jan 16-17 2004, p. 19, 2004.

J. Jaroszewski, R. Rieger, C. Jaeckel, P. Rieck, C. Hartmann, E. Grisan, A. Ruggeri. Validation of a new software for automatic endothelial cell density calculation of donor corneas. Proc. 16th Annual Meeting European Eye Bank Association, Barcelona, Spain, Jan 16-17 2004, p. 20, 2004.

P.P. Radin, E. Midena, M. Varano, E. Convento, A. Ruggeri. Automated fundus-related perimetry (microperimetry) in the follow-up of macular diseases: a new methodological approach. Proc. ARVO 2004 Annual Meeting, Fort Lauderdale (FL), USA, Apr 25-29 2004, p.B697, 2004.

A. Ruggeri, E. Grisan, J. Jaroszewski. Repeatability analysis for automatic estimation of endothelial cell density. Proc. 17th Annual Meeting European Eye Bank Association, Halle/Saal, Germany, Jan 14-16 2005, p. 21, 2005.

A. Ruggeri, E. Grisan, A. Giani. A robust procedure for vessel tracking in retinal images. Proc. ARVO 2005 Annual Meeting, Fort Lauderdale (FL), USA, May 1-5 2005, p. 1557/B326, 2005.

R. Biagi, F. Turra, D. Camposampiero, D. Ponzin, A. Ruggeri. Application of NIDEK ConfoScan-4 in eye banking. Proc. 18th Annual Meeting European Eye Bank Association, Venice, Italy, Jan 20-21 2006, p. 24, 2006.

E. Cerulli, A. Ruggeri. Automatic identification of endothelium images in ConfoScan-4 20x image sequences.Proc. 18th Annual Meeting European Eye Bank Association, Venice, Italy, Jan 20-21 2006, p. 40, 2006.

E. Zanetti, D. Ponzin, C. Amici, A. Pocobelli, A. Ruggeri. NIDEK "Eyebank" software vs eye-piece counting for the estimation of endothelial cell density. Proc. 18th Annual Meeting European Eye Bank Association, Venice, Italy, Jan 20-21 2006, p. 42, 2006.

A. Ruggeri, E. Grisan, A. Paviotti, N. Laurenti. A novel technique for the automatic estimation of endothelium cell density. Proc. 18th Annual Meeting European Eye Bank Association, Venice, Italy, Jan 20-21 2006, p. 68, 2006.

F. Scarpa,E. Grisan, A. Ruggeri. Automatic detection and measurement of sub-basal nerves in confocal microscopy of the cornea. Proc. 18th Annual Meeting European Eye Bank Association, Venice, Italy, Jan 20-21 2006, p. 69, 2006.

A. Ruggeri, E. Grisan, J. Jaroszewski, P. Rieck, E. Zanetti, D. Ponzin, C. Amici, A. Pocobelli, G. Thuret, P. Gain. Multi-center evaluation of the NIDEK "Eyebank" application for the automatic estimation of endothelial cell density. Proc. 18th Annual Meeting European Eye Bank Association, Venice, Italy, Jan 20-21 2006, p. 70, 2006.

A. Ruggeri, F. Scarpa, E. Grisan. Automatic Tracing of Subbasal Nerves in Confocal Microscopy Images. Proc. ARVO 2006 Annual Meeting, Fort Lauderdale (FL), USA, Apr 30 - May 4 2006, Nr. 1338, 2006.

A. Ruggeri, E. Grisan, J. Schroeter. Automatic estimation of corneal endothelial cell density in images from swollen organ cultured donor corneas. Proc. EVER 2006 Congress, Vilamoura, Portugal, Oct 4-8 2006, p. 47/373, 2006.

A. Ruggeri, E. Grisan, K.M. Harvey. Modern concepts of image analysis in cornea. Proc. ICER 2006, Buenos Aires, Argentina, Oct 28 - Nov 3 2006, p. 72, 2006 (invited lecture).

F. Zulian, D. Meneghesso, E. Grisan, F. Vittadello, A.B. Fortina, B. Pigozzi, R. Mancin, G. Martini, A. Ruggeri. A computerized method to assess the skin involvement in localized scleroderma. ARTHRITIS AND RHEUMATISM. vol. 54, pp. S683. 2006.

A. Ruggeri, F. Scarpa, E. Grisan, J.W. McLaren, J.C. Erie, W.M. Bourne. Evaluation of automatic corneal nerve tracing in normal and refractive surgery subjects. Proc. ARVO 2007 Annual Meeting, Fort Lauderdale (FL), USA, May 6-11 2007, Nr. 2753, 2007.

A. Ruggeri, E. Grisan. A software system for automatic estimation of corneal epithelial cell density in confocal microscopy. Proc. EVER 2007 Annual Meeting, Portoroz (SLO), Oct 3-7 2007, Nr. 2417, p.112, 2007.

A. Ruggeri, D. Fiorin. Recent advances in the analysis of non vascular features in retinal images. Proc. EVER 2007 Annual Meeting, Portoroz (SLO), Oct 3-7 2007, Nr. 3423, p.155, 2007 (invited lecture).

M.K. Smolek, S. Piermarocchi, A. Ruggeri, M. De Luca, E. Grisan. Diabetic retinopathy screening system based on a Nidek Orion automated fundus camera prototype. Proc. AAO 2007 Annual Meeting, 2007.
S. Duench, T. Simpson, A. Tiso, E. Grisan, A. Ruggeri, D. Fonn. Measurement of Average Real-Time Red Blood Cell Velocity in Conjunctival Vessels. Proc. ARVO 2008 Annual Meeting, Fort Lauderdale (FL), USA, Apr 27 - May 1 2008, Nr. 6051, 2008.

M.K. Smolek, S. Vujosevic, S. Piermarocchi, E. Midena, T. Peto, M. De Luca, E. Grisan, A. Ruggeri, S.D. Klyce. An Expert System for Diabetic Retinopathy Screening With a Non-Mydriatic, Operator-Free Fundus Camera. Proc. ARVO 2008 Annual Meeting, Fort Lauderdale (FL), USA, Apr 27 - May 1 2008, Nr. 2725, 2008.

A. Ruggeri, F. Scarpa. Automatic Estimation of Keratocyte Density in Confocal Microscopy of the Cornea. Proc. ARVO 2008 Annual Meeting, Fort Lauderdale (FL), USA, Apr 27 - May 1 2008, Nr. 3929, 2008.

A. Ruggeri, L. Tramontan, E. Grisan. Automatic estimation of the arteriolar-to-venular diameter ratio (AVR) in retinal images. Proc. EVER 2008 Annual Meeting, Portoroz (SLO), Oct 1-4 2008, Nr. 6446, p.157, 2008.

A. Ruggeri, D. Fiorin. ROPnet, a Web-system for vessel caliber and tortuosity estimation in ROP retinal images. Proc. ARVO 2009 Annual Meeting, Fort Lauderdale (FL), USA, May 3-7, 2009, Nr. 3133, 2009.

L. Grunwald, M.D. Mills, G.S. Ying, K.A. Karp, J.E. Grunwald, Y. Dai, D. Fiorin, A. Ruggeri, G.E. Quinn. Retinal vessel width in infants at risk for retinopathy of prematurity between 31 and 34 weeks post-menstrual age. Proc. ARVO 2009 Annual Meeting, Fort Lauderdale (FL), USA, May 3-7, 2009, Nr. 3134, 2009.

A. Ruggeri, L. Tramontan, E. Poletti, D. Fiorin. A computerized system for CRAE, CRVE and AVR estimation in retinal images. Proc. ARVO 2010 Annual Meeting, Fort Lauderdale (FL), USA, May 2-6, 2010, Nr. 5343, 2010.

P. Kasae, A. Ruggeri. Automated identification of optic disc in retinal images using local entropy. Proc. ARVO 2010 Annual Meeting, Fort Lauderdale (FL), USA, May 2-6, 2010, Nr. 5344, 2010.

L. Grunwald, G.S. Ying, G.E. Quinn, Y. Dai, K.A. Karp , D. Fiorin, A. Ruggeri, J.E. Grunwald, M.D. Mills. Retinal vessel tortuosity in infants at risk for retinopathy of prematurity between 31 and 34 weeks post-menstrual age. Proc. ARVO 2010 Annual Meeting, Fort Lauderdale (FL), USA, May 2-6, 2010, Nr. 5919, 2010.
E.A. DeCarlo, G.S. Ying, G.E. Quinn, D. Fiorin, A. Ruggeri, K. Karp, M.D. Mills. Vessel Width in Type 1 ROP: Zone I vs Zone II, Journal of AAPOS, Vol. 14(1), p. E15, 2010.

A. Ruggeri, E. Poletti, D. Fiorin, L. Tramontan, T. Peto. A Web-based System for Vessel Tortuosity Estimation in Retinal Images. Proc. ARVO 2011 Annual Meeting, Fort Lauderdale (FL), USA, May 1-5, 2011, Nr. 6136, 2011.

A. Ruggeri, E. Poletti. Quantitative Estimation of Vessel Tortuosity in Wide-field ROP Images. Proc. ARVO 2012 Annual Meeting, Fort Lauderdale (FL), USA, May 6-9, 2012, Nr. 2179, 2012.

A. Ruggeri, E. Poletti. Best Frames Selection and Montaging in Wide-field ROP Images. Proc. ARVO 2013 Annual Meeting, Seattle (WA), USA, May 5-9, 2013, Nr. 3629, 2013.

A. Ruggeri, E. Poletti. AUTOMATIC ESTIMATION OF MORPHOMETRIC PARAMETERS IN CORNEAL ENDOTHELIUM IMAGES. Proc. ARVO 2014 Annual Meeting, Orlando (FL), USA, May 4-8, 2014, Nr. 2070, 2014.

E. Poletti, A. Ruggeri. WIDE-RANGE MOSAIC OF CORNEAL SUB-BASAL NERVES IMAGES BY AUTOMATIC MONTAGING. Proc. ARVO 2014 Annual Meeting, Orlando (FL), USA, May 4-8, 2014, Nr. 2141, 2014.

P. Guimaraes, J. Wigdahl, E. Poletti, N. Lagali, A. Ruggeri. A fully-automatic fast technique to trace sub-basal layer nerves in corneal images. Proc. ARVO 2014 Annual Meeting, Orlando (FL), USA, May 4-8, 2014, Nr. 2454, 2014.

J. Wigdahl, E. Poletti, P. Guimaraes, A. Ruggeri. CANE (CORNEAL NERVE EDITOR): A User-Friendly Unified Computerized System for Recognizing, Editing and Analyzing Corneal Sub-Basal Nerves Image. Proc. ARVO 2014 Annual Meeting, Orlando (FL), USA, May 4-8, 2014, Nr. 4864, 2014.

S.N. Patel, R.V.P. Chan, A. Ruggeri, E. Poletti, E. Ataer-Cansizoglu, J. Kalpathy-Cramer, K. Jonas, S. Ostmo, M.F. Chiang. Functional modifications of retinal images in quantitative plus disease diagnosis of retinopathy of prematurity. Proc. ARVO 2014 Annual Meeting, Orlando (FL), USA, May 4-8, 2014, Nr. 5929, 2014.

R.A Badian, T. Paaske Utheim, S. Allgeier, B. Koehler, A. Ruggeri, E. Poletti, P. Guimaraes, N.S. Lagali. Quantitative Analysis of Corneal Subbasal Nerve Plexus and Inflammatory Cells in Large-area Mosaics Obtained by In Vivo Confocal Microscopy. Proc. ARVO 2015 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.56, 1637, Jun 2015.

P. Guimaraes, L. Frizziero, J.C. Wigdahl, E. Midena, A. Ruggeri. Fully-automatic segmentation of conjunctival blood vessels. Proc. ARVO 2015 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.56, 1970, Jun 2015.

A. Ruggeri, E. Poletti, N.S. Lagali. Clinical grading of corneal subbasal nerve tortuosity. Proc. ARVO 2015 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.56, 1963, Jun 2015.

F. Scarpa, A. Ruggeri. Automatic segmentation of corneal endothelial cells by a genetic algorithm. Proc. ARVO 2015 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.56, 1960, Jun 2015.

J.C. Wigdahl, P. Guimaraes, E. Poletti, A. Ruggeri. ReVMS (Retinal Vasculature Measurement System). Proc. ARVO 2015 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.56, 5260, Jun 2015.

N.S. Lagali; S. Allgeier; P. Guimaraes; R.A. Badian; A. Ruggeri; B. Koehler; T. Paaske Utheim; B. Bourghardt Peebo; M. Peterson; L. Dahlin; O. Rolandsson. Analysis of corneal subbasal nerve plexus from wide-area mosaics in healthy subjects and in type 2 diabetics. Proc. ARVO 2016 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.57, 6158, Sep 2016.

P. Guimaraes; A. Ruggeri. Automatic estimation of short- and long-range tortuosity of corneal subbasal nerves. Proc. ARVO 2016 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.57, 1923, Sep 2016.

F. Scarpa; A. Ruggeri. Development of a totally automated method for the reliable morphometry of human corneal endothelium. Proc. ARVO 2016 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.57, 1936, Sep 2016.

J.C. Wigdahl; R. Annunziata; L. Hughes; S. Borooah; A. Ruggeri; E. Trucco. New Public Retinal Image Database for Tortuosity Evaluation. Proc. ARVO 2016 Annual Meeting, Investigative Ophthalmology & Visual Science, Vol.57, 3399, Sep 2016.

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Abstracts in italian conference proceedings

S. Del Prato, C. Cobelli, P. Moghetti, P. Tessari, A. Ruggeri, A. Lapolla, M. Muggeo. Riduzione della utilizzazione periferica del glucosio nel diabete tipo I. Atti del IX Congresso Nazionale della Societa' Italiana di Diabetologia, Bari, 26-29 maggio 1982, Giornale Italiano di Diabetologia, 2 : 221, 1982 e Diabetologia, 23 : 296, 1982.

R. Vettor, C. Macor, C. Martini, P. Mazzonetto, C. De Palo, N. Sicolo, A. Ruggeri, C. Cobelli, G. Federspil. Secrezione insulinica e metabolismo periferico del glucosio nel soggetto acromegalico. Atti del XCII Congresso Nazionale della Societa' Italiana di Medicina Interna, Roma, 15-10 ottobre 1991, p. 132, 1991.

R. Vettor, C. Macor, C. Martini, C. De Palo, P. Rocchini, N. Sicolo, A. Ruggeri, C. Cobelli, G. Federspil. Studio della secrezione insulinica e del metabolismo periferico del glucosio nell'acromegalia. Atti del XXIV Congresso Nazionale della Societa' Italiana di Endocrinologia, Genova, 12-15 maggio 1992, J. Endocrinol. Invest., 15 suppl.1: 261, 1992.

M.G. Artioli, E. Bonora, M. Zenere, F. Saggiani, A. Ruggeri e C. Cobelli. Insulino-resistenza, glucosio-resistenza, secrezione beta-cellulare e metabolismo dell'insulina nell'obesita' umana: rapporti con il grasso totale e regionale. Atti del XIV Congresso Nazionale della Societa' Italiana di Diabetologia, Genova, 17-20 maggio 1992, Il Diabete, 4 suppl. 1: 105, 1992.

F. Carmignoto, A. Ruggeri, R. Matano, O. Faggionato. Un sistema esperto per la valutazione dei risultati di laboratorio in trial clinici. Atti del ATB '92 Conference Satellite Meeting "Sistemi integrati nel laboratorio", Milano, 24 novembre 1992, p. 16, 1992.

A.M.R. Matano, F. Carmignoto, A. Ruggeri. Tollerabilita' del farmaco: utilizzo di un sistema esperto. Atti del III Congresso Nazionale Societa' Italiana per la Verifica e lo Sviluppo dei Farmaci Post-Registrazione, Roma, 29-30 gennaio 1993, p. 78, 1993.

C. Macor, R. Vettor, S. Favro, P. Mazzonetto, A. Ruggeri, G. Federspil. Influenza del tessuto adiposo viscerale sulla dinamica secretoria beta-cellulare, sulla sensibilita' periferica all'insulina e sulla termogenesi postprandiale nel soggetto obeso. Atti del XV Congresso Nazionale della Societa' Italiana di Diabetologia, Roma, 18-22 maggio 1994, Il Diabete, 6 suppl. 1: 106, 1994.

A. Ruggeri. Un software per la classificazione automatica di lesioni retiniche. Atti del XVIII Convegno Annuale della Societa' Oftalmologica Triveneta, Verona, 14 giugno 2002, p.11, 2002.

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